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2022

Biao Chen, Wenjie Ma, Xu Long, Hong Cheng, Huanhuan Sun, Jin Huang, Ruichen Jia, Xiaoxiao He,* and Kemin Wang*Membrane Protein and Extracellular Acid Heterogeneity-Driven Amplified DNA Logic Gate Enables Accurate and Sensitive Identification of Cancer Cells, Anal. Chem. 2022, 94, 2502−2509.

Ruichen Jia, Yitan Wang, Wenjie Ma, Jin Huang, Huanhuan Sun, Biao Chen, Hong Cheng, Xiaoxiao He,* and Kemin Wang*Activatable Dual Cancer-Related RNA Imaging and Combined GeneChemotherapy through the Target-Induced Intracellular Disassembly of Functionalized DNA Tetrahedron, Anal. Chem. 2022, 94, 59375945.

Ruichen Jia, Yitan Wang, Wenjie Ma, Jin Huang, Huanhuan Sun, Biao Chen, Hong Cheng, Xiaoxiao He,* and Kemin Wang*Activatable Dual Cancer-Related RNA Imaging and Combined GeneChemotherapy through the Target-Induced Intracellular Disassembly of Functionalized DNA Tetrahedron, Anal. Chem. 2022, 94, 59375945.

Hongqiang Wang 1, Xiaofeng Liu 1, Liyuan Zou , Wenjing Mei , Qingqing Zou , Xiaohai Yang , Qing Wang *, Kemin Wang **Polymer-assisted Au@PDA nanoparticles lyophilized powder with high stability and low adsorption and its application in colorimetric biosensing, Analytica Chimica Acta, 2022, 1220, 339995.

Huizhen Wang, Jiahao Zeng, Jin Huang, Hong Cheng, Biao Chen, Xing Hu, Xiaoxiao He,* Yue Zhou,* and Kemin Wang*A Self-Serviced-Track 3D DNA Walker for Ultrasensitive Detection of Tumor Exosomes by Glycoprotein Profiling, Angew. Chem. Int. Ed. 2022, 61, e202116932.

Shiyuan Liu, Zhenxiang Liu, Huimin Wang, Jiaoli Wang, Ruiting Liu, Kemin Wang and Jin Huang *A novel FRET-based dendritic hybridization chain reaction for tumour-related mRNA imaging, Chem. Commun., 2022, 58: 1414-1417.

Huimin Wang, Jiaoli Wang, Ruiting Liu, Zhenxiang Liu, Kemin Wang and Jin Huang *Auto-cycling primer extension for amplified microRNA detection, Chem. Commun., 2022, 58, 6020-6023.

Jing Li and Jin Huang*Fuel-Powered DNA Nanomachines for Biosensing and Cancer Therapy, ChemPlusChem, 2022, 87, e202200098 (1 of 14).

Lie Li, Jie Wang, Huishan Jiang, Xiaohong Wen, Mei Yang, Suping Li, Qiuping Guo*, Kemin WangDNA tetrahedron-based split aptamer probes for reliable imaging of ATP in living cells*, Journal Pre-proof, 2022, https://doi.org/10.1016/j.cclet.2022.05.020.

Min Hou, Dinggeng He,∗, Huizhen Wang, Jin Huang, Hong Cheng, Kejin Wan, Hung-Wing Li , Zifeng Tang, Xiaoxiao He,∗, Kemin Wang,∗Simultaneous and multiplex detection of exosomal microRNAs based on the asymmetric Au@Au@Ag probes with enhanced Raman signal, Chinese Chemical Letters, 2022, 33: 3183-3187.

Jiaqi Xu , Rundong Jiang , Yuxin Feng, Zhuqing Liu , Jin Huang, Changbei Ma ⇑, Kemin WangFunctional nucleic acid-based fluorescent probes for metal ion detection, Coordination Chemistry Reviews,2022, 459, 214453.

Jing Li, Shiyuan Liu, Jiaoli Wang, Ruiting Liu, Xiaohai Yang, Kemin Wang and Jin Huang ,Photocaged amplified FRET nanoflares: spatiotemporal controllable of mRNA-powered nanomachines for precise and sensitive microRNA imaging in live cells, Nucleic Acids Research, 2022, 50, 7: 2-16.

Jing Li, Shiyuan Liu, Jiaoli Wang, Ruiting Liu, Xiaohai Yang, Kemin Wang and Jin Huang ,Photocaged amplified FRET nanoflares: spatiotemporal controllable of mRNA-powered nanomachines for precise and sensitive microRNA imaging in live cells, Nucleic Acids Research, 2022, 50, 7: 2-16.

Yuzhen Ouyang , Yifan Liu, Yuan Deng, Hailun He, Jin Huang **, Changbei Ma,*Kemin WangRecent advances in biosensor for DNA glycosylase activity detection, Talanta, 2022, 239, 123144.

Fengzhou Xu, Zhenzhen Qiao, Lan Luo, Xiaoxiao He, Yanli Lei, Jinlu Tang, Hui Shi **, Kemin Wang b,*A label-free cyclic amplification strategy for microRNA detection by coupling graphene oxide-controlled adsorption with superlong poly (thymine)-hosted fluorescent copper nanoparticles, Talanta, 2022, 243, 123323.

Jin Huang, Yuchen Wu, Hui He, Wenjie Ma, Jianbo Liu, Hong Cheng, Huanhuan Sun, Xiaoxiao He*, Kemin Wang*Acidic microenvironment triggered in situ assembly of activatable three-arm aptamer nanoclaw for contrast-enhanced imaging and tumor growth inhibition in vivo, Theranostics, 2022, 12, 7: 3474-3487.

2021

Yanwen Zhang, Yufeng Chen, Xiaohai Yang, Xiaoxiao He, Mei Li, Songyang Liu, Kemin Wang, Jianbo Liu*, Stephen Mann.*Giant coacervate vesicles as an integrated approach to cytomimetic modelingJournal of the American Chemical Society20211432866-2874.

Hui Chen,# Li Zhou,# Chunying Li, Xiaoxiao He, Jin Huang, Xiaohai Yang, Hui Shi,* Kemin Wang, Jianbo Liu.*Controlled dimerization of artificial membrane receptors for transmembrane signal transduction”, Chemical Science, 202112: 8224-8230.

Qiaoshu Chen, Meiling Jian, Hui Chen, Bing Zhou, Hui Shi, Xiaohai Yang, Kemin Wang, Jianbo Liu.*“Design of lipophilic split aptamers as artificial carriers for transmembrane transport of adenosine triphosphate”, CCS Chemistry20213: 144-153.

Yanwen Zhang, Yu Yao, Songyang Liu, Yufeng Chen, Shaohong Zhou, Kemin Wang, Xiaohai Yang,* Jianbo Liu.*Coacervate microdroplet protocells-mediated gene transfection for nitric oxide production and induction of cell apoptosis”,  Journal of Materials Chemistry B, 202199784-9793.

Yanwen Zhang, Yu Yao, Songyang Liu, Yufeng Chen, Shaohong Zhou, Kemin Wang, Xiaohai Yang,* Jianbo Liu.*“Coacervate microdroplet protocells-mediated gene transfection for nitric oxide production and induction of cell apoptosis”, Journal of Materials Chemistry B, 202199784-9793.

 Yu Yao#, Yanwen Zhang#, Li Li, Yan Huang, Xiaohai Yang, Zhihong Peng,* Kemin Wang, Jianbo Liu.*Photothermally activated coacervate model protocells as signal transducers endow mammalian cells with light sensitivity”, Advanced Biology20215, 2100695.

Chunying Li, Hui Chen, Xiaohai Yang,* Kemin Wang, Jianbo Liu.*An ion transport switch based on light-responsive conformation-dependent G-quadruplex transmembrane channels”, Chemical Communications, 2021578214-8217.

Yufeng Chen, Yanwen Zhang, Mei Li, Songyang Liu, Xiaohai Yang, Kemin Wang, Stephen Mann,* Jianbo Liu.*Self-immobilization of coacervate droplets by enzyme-mediated hydrogelation”, Chemical Communications2021575438-5441.

Lei Luo, Min Wang, Yuan Zhou, Dongliu Xiang, Qing Wang, Jin Huang, Jianbo Liu, Xiaohai Yang,*and Kemin Wang.*Ratiometric Fluorescent DNA Nanostructure for Mitochondrial ATP Imaging in Living Cells Based on Hybridization Chain Reaction”, Analytical Chemistry202193: 6715-6722.

Liyuan Zou , Xiaofeng Liu , Yuan Zhou , Wenjing Mei , Qing Wang *, Xiaohai Yang *, Kemin Wang.Optical fiber amplifier and thermometer assisted point-of-care biosensor for detection of cancerous exosomes”, Sensors and Actuators: B. Chemical2022351130893.

Wenjing Mei, Xiaofeng Liu, Liyuan Zou, Qing Wang *, Xiaohai Yang *, Kemin Wang.Microcapillary-based multicolor assay for quantitative and sensitive point-of-care testing of proteins”, Biosensors and Bioelectronics2021189113370.

Jing Li,† Anmin Wang,† Xiaohai Yang, Kemin Wang, and Jin Huang.*Orderly Assembled, Self-Powered FRET Flares for MicroRNA Imaging in Live Cells”, Analytical Chemistry2021936270-6277.

Qing Lin, Shijun Cai, Bing Zhou, Kemin Wang, Lixin Jian*, Jin Huang*.Dual-MicroRNA-regulation of singlet oxygen generation by a DNA-tetrahedron-based molecular logic device”, Chemical Communications2021573873-3876.

Shijun Cai, Jiaoli Wang, Jing Li, Bing Zhou, Chunmei He, Xiangxian Meng*, Jin Huang*, Kemin Wang.A self-assembled DNA nanostructure as a FRET nanoflare for intracellular ATP imaging”, Chemical Communications, 2021, 576257-6260.

Yehua Liu, Zhenxiang Liu, Ruiting Liu, Kemin Wang, Hui Shi * andJin Huang*.A MnO2 nanosheet-mediated photo-controlled DNAzyme for intracellular miRNA cleavage to suppress cell growth”, Analyst20211463391-3398.

Yanli Lei, Jinlu Tang, Xiaoxiao He, Hui Shi,* Yu Zeng, Haiyan Sun, and Kemin Wang.*In Situ Modulating DNAzyme Activity and Internalization Behavior with Acid-Initiated Reconfigurable DNA Nanodevice for Activatable Theranostic”, Analytical Chemistry2021935629-5634.

Wenjie Ma, Biao Chen, Ruichen Jia, Huanhuan Sun, Jin Huang, Hong Cheng, Huizhen Wang, Xiaoxiao He,* and Kemin Wang.*In Situ Hand-in-Hand DNA Tile Assembly: A pH-Driven and Aptamer Targeted DNA Nanostructure for TK1 mRNA Visualization and Synergetic Killing of Cancer Cells”, Analytical Chemistry2021, 9310511-10518.

Hong Cheng, Pansen Hui, Jiaxin Peng, Wei Li, Wenjie Ma, Huizhen Wang, Jin Huang, Xiaoxiao He,* and Kemin Wang.*Enzymatic Behavior Regulation-Based Colorimetric and Electrochemiluminescence Sensing of Phosphate Using the Cobalt Oxyhydroxide Nanosheet”,  Analytical Chemistry2021936770-6778.

Wenjie Ma, Huanhuan Sun, Biao Chen, Ruichen Jia, Jin Huang, Hong Cheng, Xiaoxiao He,* Mingmin Huang,* and Kemin Wang.*Engineering a Facile Aptamer “Molecule-Doctor” with HairpinContained I‑Motif Enables Accurate Imaging and Killing of Cancer Cells”, Analytical Chemistry20219314552-14559.

Yuqin Zeng, Lu Sun, Dou Du, Xiaoxiao He,* and Liyang Shi.*Lanthanide-Bisphosphonate Coordination Chemistry: Biocompatible Fluorescent Labeling Strategy for Hydrogel”, ACS Applied Bio Materials202141057-1064.

Xue Yang, Man Li, Jinying Liang, Xueyan Hou, Xiaoxiao He,* and Kemin Wang.*NIR-Controlled Treatment of Multidrug-Resistant Tumor Cells by Mesoporous Silica Capsules Containing Gold Nanorods and Doxorubicin”, ACS Applied Materials & Interfaces20211314894-14910.

Huanhuan Sun, Wenjie Ma, Shuangdi Duan, Jin Huang, Ruichen Jia, Hong Cheng, Biao Chen, Xiaoxiao He*, Kemin Wang*.An endogenous stimulus detonated nanocluster-bomb for contrast-enhanced cancer imaging andcombination therapy”, Chemical Science20211212118-12129.

Shuangdi Duan 1, Jiaxin Peng 1, Hong Cheng, Wei Li, Ruichen Jia, Jinquan Liu, Xiaoxiao He **, Kemin Wang *.A label-free and homogenous electrochemical assay for matrix metalloproteinase 2 activity monitoring in complex samples based on electrodes modified with orderly distributed mesoporous silica films”,Talanta, 2021231122418.

Yujian Zou, Xiaohong Wenb, Dan Ling, Dongshan Zhang, Lei Lei, Dan Zhu, Honghui Wang, Kemin Wang, Qiuping Guo,∗Hemin Nie.∗Precise monitoring of mesenchymal stem cell homing to injured kidney with an activatable aptamer probe generated by cell-SELEX”,Applied Materials Today202122, 100974.

Lie Li,† Jun Wan,† Xiaohong Wen, Qiuping Guo,* Huishan Jiang, Jie Wang, Yazhou Ren, and Kemin Wang.*Identification of a New DNA Aptamer by Tissue-SELEX for Cancer Recognition and Imaging”,Analytical Chemistry2021937369-7377.

Lie Li, Yazhou Ren, Xiaohong Wen, Qiuping Guo,* Jie Wang, Suping Li, Mei Yang, and Kemin Wang.*Endogenous miRNA-Activated DNA Nanomachine for Intracellular miRNA Imaging and Gene Silencing”,Analytical Chemistry20219313919-13927.

Lie Li, Huishan Jiang, Xiangxian Meng, Xiaohong Wen, Qiuping Guo *, Zenghui Li, Jie Wang, Yazhou Ren, Kemin Wang *.Highly sensitive detection of cancer cells via split aptamer mediated proximity-induced hybridization chain reaction”,Talanta, 2021, 223: 121724.  

2020

Songyang Liu, Yanwen Zhang, Mei Li, Li Xiong, Zijian Zhang, Xiaohai Yang, Xiaoxiao He, Kemin Wang, Jianbo Liu*  and Stephen Mann* , "Enzyme-mediated nitric oxide production in vasoactive erythrocyte membrane-enclosed coacervate protocells", Nature Chemistry, 2020, 12(12): 1165-1173. DOI: 10.1038/s41557-020-00585-y.

Zhenwei Tang, Jin Huang, Hailun He, Changbei Ma*, Kemin Wang*, "Contributing to liquid biopsy: Optical and electrochemical methods in cancer biomarker analysis", Coordination Chemistry Reviews, 2020, 415: 213317-213340. DOI:10.1016/j.ccr.2020.213317.

Jianbo Liu,* Liangfei Tian, Yan Qiao, Shaohong Zhou, Avinash J. Patil, Kemin Wang, Mei Li,* and Stephen Mann*, "Hydrogel-immobilized coacervate droplets as modular microreactor assemblies", Angewandte Chemie-International Edition, 2020, 59(17): 6853-6859. DOI:10.1002/anie.201916481.

Jing Li, Jiaoli Wang, Shiyuan Liu, Nuli Xie, Ke Quan, Yanjing Yang, Xiaohai Yang, Jin Huang,* and Kemin Wang*, "Amplified FRET nanoflares: An endogenous mRNA-powered nanomachine for intracellular microRNA imaging", Angewandte Chemie-International Edition, 2020, 59(45): 20104-20111. DOI:10.1002/anie.202008245.

Yanwen Zhang, Songyang Liu, Yu Yao, Yufeng Chen, Shaohong Zhou, Xiaohai Yang, Kemin Wang,* and Jianbo Liu*, "Invasion and defense interactions between enzyme-active liquid coacervate protocells and living cells", Small, 2020, 16(29): 2002073. DOI:10.1002/smll.202002073.

Ke Quan, Cuiping Yi, Xiaohai Yang, Xiaoxiao He, Jin Huang*, Kemin Wang*, "FRET-based nucleic acid probes: Basic designs and applications in bioimaging", Trends in Analytical Chemistry, 2020, 124: 115784. DOI:10.1016/j.trac.2019.115784.

Nuli Xie, Haiyan Wang, Ke Quan, Feng Feng*, Jin Huang*, Kemin Wang*, "Self-assembled DNA-based geometric polyhedrons: Construction and applications", Trends in Analytical Chemistry, 2020, 126: 115844. DOI:10.1016/j.trac.2020.115844.

Yufeng Chen, Min Yuan, Yanwen Zhang, Songyang Liu, Xiaohai Yang, Kemin Wang* and Jianbo Liu*, "Construction of coacervate-in-coacervate multi-compartment protocells for spatial organization of enzymatic reactions", Chemical Science, 2020, 11(32): 8617-8625. DOI:10.1039/d0sc03849k.

Yaqing Xu, Meitao Deng, Haitao Zhang, Sha Tan, Dan Li, Shaoyuan Li, Lei Luo, Guofu Liao, Qing Wang, Jin Huang, Jianbo Liu, Xiaohai Yang,* and Kemin Wang*, "Selection of affinity reagents to neutralize the hemolytic toxicity of melittin based on a self-assembled nanoparticle library", ACS Applied Materials & Interfaces, 2020, 12(14): 16040-16049. DOI:10.1021/acsami.0c00303.

Xiaofeng Liu, Jinan Qin, Xiaoyu Zhang, Liyuan Zou, Xiaohai Yang, Qing Wang,* Yan Zheng, Wenjing Mei and Kemin Wang*, "The mechanisms of HSA@PDA/Fe nanocomposites with enhanced nanozyme activity and their application in intracellular H2O2 detection", Nanoscale, 2020, DOI: 10.1039/DONR05732K.

Chunying Li, Hui Chen, Qiaoshu Chen, Hui Shi,* Xiaohai Yang, Kemin Wang, and Jianbo Liu*, "Lipophilic G-quadruplex isomers as biomimetic ion channels for conformation-dependent selective transmembrane transport", Analytical Chemistry, 2020, 92(14): 10169-10176. DOI:10.1021/acs.analchem.0c02222.

Liyuan Zou, Zhaoxing Wu, Xiaofeng Liu, Yan Zheng, Wenjing Mei, Qing Wang,* Xiaohai Yang,* and Kemin Wang, "DNA hydrogelation-enhanced imaging ellipsometry for sensing exosomal micrornas with a tunable detection range", Analytical Chemistry, 2020, 92(17): 11953-11959. DOI:10.1021/acs.analchem.0c02345.

Jinlu Tang, Yanli Lei, Xiaoxiao He, Jianbo Liu, Hui Shi,* and Kemin Wang*, "Recognition-driven remodeling of dual-split aptamer triggering in situ hybridization chain reaction for activatable and autonomous identification of cancer cells", Analytical Chemistry, 2020, 92(15): 10839-10846. DOI:10.1021/acs.analchem.0c02524.

Shaoyuan Li, Yan Zheng, Qingqing Zou, Guofu Liao, Xiaofeng Liu, Liyuan Zou, Xiaohai Yang,* Qing Wang,* and Kemin Wang, "Engineering and application of a myoglobin binding split aptamer", Analytical Chemistry, 2020, 92(21): 14576-14581. DOI:10.1021/acs.analchem.0c02869.

Biao Chen, Yitan Wang, Wenjie Ma, Hong Cheng, Huanhuan Sun, Huizhen Wang, Jin Huang, Xiaoxiao He,* and Kemin Wang*, "A mimosa-inspired cell-surface-anchored ratiometric DNA nanosensor for high-resolution and sensitive response of target tumor extracellular pH", Analytical Chemistry, 2020, 92(22): 15104-15111. DOI:10.1021/acs.analchem.0c03250.

Yan Zheng, Xiuhua Geng, Xiaohai Yang, Shaoyuan Li, Yaqin Liu, Xiaofeng Liu, Qing Wang,* Kemin Wang,* Ruichen Jia, and Yao Xu, "Exploring interactions of aptamers with Aβ40 amyloid aggregates and its application: Detection of amyloid aggregates", Analytical Chemistry, 2020, 92(3): 2853-2858. DOI:10.1021/acs.analchem.9b05493.

Yanjing Yang, Yao He, Zhiwei Deng, Jiacheng Li, Jin Huang,* and Shian Zhong*, "Intelligent nanoprobe: Acid-responsive drug release and in situ evaluation of its own therapeutic effect", Analytical Chemistry, 2020, 92(18): 12371-12378. DOI:10.1021/acs.analchem.0c02099.

Guofu Liao, Xiaofeng Liu, Xiaohai Yang, Qing Wang, Xiuhua Geng, Liyuan Zou, Yaqin Liu, Shaoyuan Li, Yan Zheng, Kemin Wang, "Surface plasmon resonance assay for exosomes based on aptamer recognition and polydopamine-functionalized gold nanoparticles for signal amplification", Mikrochimica Acta, 2020, 187(4): 251. DOI:10.1007/s00604-020-4183-1.

Xiaofeng Liu, Zhaoxing Wu, Xiaohai Yang, Qing Wang & Liyuan Zou, Wenjing Mei, Yan Zheng, Kemin Wang, "Photothermal and fluorescent dual-mode assay based on the formation of polydopamine nanoparticles for accurate determination of organophosphate pesticides", Mikrochimica Acta, 2020, 187(12): 652-657. DOI:10.1007/s00604-020-04629-5.

Anmin Wang, Qing Lin, Shiyuan Liu, Jing Li, Jiaoli Wang, Ke Quan, Xiaohai Yang, Jin Huang* and Kemin Wang, "Aptamer-tethered self-assembled FRET-flares for microRNA imaging in living cancer cells", Chemical Communications, 2020, 56(16): 2463-2466. DOI:10.1039/c9cc09919k.

Lei Luo, Wenshan Li, Dongliu Xiang, Yanyun Ma, Yuan Zhou, Yaqing Xu, Nandi Chen, Qing Wang, Jin Huang, Jianbo Liu, Xiaohai Yang* and Kemin Wang*, "Sensitive and specific detection of tumour cells based on a multivalent DNA nanocreeper and a multiplexed fluorescence supersandwich", Chemical Communications, 2020, 56(25): 3693-3696. DOI:10.1039/c9cc08618h.

Qing Lin, Anmin Wang, Shiyuan Liu, Jing Li, Jiaoli Wang, Ke Quan, Xiaohai Yang, Jin Huang* and Kemin Wang, "A DNA tetrahedron-based molecular computation device for the logic sensing of dual microRNAs in living cells", Chemical Communications, 2020, 56(39): 5303-5306. DOI:10.1039/d0cc01231a.

Jing Li, Shijun Cai, Bing Zhou, Xiangxian Meng, Qiuping Guo, Xiaohai Yang, Jin Huang* and Kemin Wang*, "Photocaged FRET nanoflares for intracellular microRNA imaging", Chemical Communications, 2020, 56(45): 6126-6129. DOI:10.1039/d0cc02395g.

Yanan Wu, Jing Li, Ke Quan, Xiangxian Meng, Xiaohai Yang, Jin Huang* and Kemin Wang, "A DNAzyme cascade for amplified detection of intracellular miRNA", Chemical Communications, 2020, 56(70): 10163-10166. DOI:10.1039/d0cc02847a.

Jiaoli Wang, Jing Li, Shiyuan Liu, Xiangxian Meng, Xiaohai Yang, Jin Huang* and Kemin Wang*, "Amplified and logic platform for cell identification", Chemical Communications, 2020, 56(76): 11267-11270. DOI:10.1039/d0cc04159a.

Huizhen Wang, Kejing Wan, Yue Zhou, Xiaoxiao He,* Dinggeng He,* Hong Cheng, Jin Huang, Ruichen Jia and Kemin Wang*, "A three-dimensional multipedal DNA walker for the ultrasensitive detection of tumor exosomes", Chemical Communications, 2020, 56(85): 12949-12952. DOI:10.1039/d0cc04360e.

Nandi Chen, Harikrishna Kommidi, Hua Guo, Amy P. Wu, Ziming Zhang, Xiaohai Yang, Ligang Xia⁎, Feifei An⁎, Richard Ting⁎, "A lysosome specific, acidic-pH activated, near-infrared bodipy fluorescent probe for noninvasive, long-term, in vivo tumor imaging", Materials Science & Engineering C, 2020, 111: 110762. DOI:10.1016/j.msec.2020.110762.

Zenghui Li, Baoyin Yuan, Xiaoxia Lin, Xiangxian Meng, Xiaohong Wen, Qiuping Guo∗, Lie Li, Huishan Jiang, Kemin Wang∗, "Intramolecular trigger remodeling-induced HCR for amplified detection of protein-specific glycosylation", Talanta, 2020, 215: 120889. DOI:10.1016/j.talanta.2020.120889.

Lie Li, Huishan Jiang, Xiangxian Meng, Xiaohong Wen, Qiuping Guo*, Zenghui Li, Jie Wang, Yazhou Ren, Kemin Wang*, "Highly sensitive detection of cancer cells via split aptamer mediated proximity-induced hybridization chain reaction", Talanta, 2021, 223: 121724. DOI:10.1016/j.talanta.2020.121724.

Yaqin Liu, Yan Zheng, Shaoyuan Li, Jinhan Li, Xiaoyu Du, Yanyun Ma, Guofu Liao, Qing Wang*, Xiaohai Yang, Kemin Wang*, "Contradictory effect of gold nanoparticle-decorated molybdenum sulfide nanocomposites on amyloid-β-40 aggregation", Chinese Chemical Letters, 2020, DOI: 10.1016/j.cclet.2020.04.052.

Anman Zhang, Luo Hai, Tianzheng Wang, Hong Cheng, Man Li, Xiaoxiao He*, Kemin Wang*, "NIR-triggered drug delivery system based on phospholipid coated ordered mesoporous carbon for synergistic chemo-photothermal therapy of cancer cells", Chinese Chemical Letters, 2020, DOI: 10.1016/j.cclet.2020.04.035.

Ri Wu, Huizhen Wang, Luo Hai, Tianzheng Wang, Min Hou, Dinggeng He*, Xiaoxiao He*, Kemin Wang*, "A photosensitizer-loaded zinc oxide-polydopamine core-shell nanotherapeutic agent for photodynamic and photothermal synergistic therapy of cancer cells", Chinese Chemical Letters, 2020, 31(1): 189-192. DOI:10.1016/j.cclet.2019.05.004.

Yan Huang, Haifeng Li, Xiaoxiao He, Xiaohai Yang, Li Li, Songyang Liu, Zhen Zou, Kemin Wang*, Jianbo Liu*, "Near-infrared photothermal release of hydrogen sulfide from nanocomposite hydrogels for anti-inflammation applications", Chinese Chemical Letters, 2020, 31(3): 787-791. DOI:10.1016/j.cclet.2019.05.025.

Jing Li, Ke Quan, Yanjing Yang, Xiaohai Yang, Xiangxian Meng, Jin Huang* and Kemin Wang*, "Engineering DNAzyme cascade for signal transduction and amplification", Analyst, 2020, 145(5): 1925-1932. DOI:10.1039/c9an02003a.

Shanzi Zou, Yanli Lei,* Wenjie Ma, Biao Chen, Hong Cheng, Ruichen Jia, Zenghui Li, Xiaoxiao He* and Kemin Wang*, "Extracellular pH-manipulated in situ reconfiguration of aptamer functionalized DNA monomer enables specifically improved affinity, detection and drug delivery", Analyst, 2020, 145(7): 2562-2569. DOI:10.1039/d0an00101e.

Huizhen Wang, Dinggeng He, Kejing Wan, Xiaowu Sheng, Hong Cheng, Jin Huang, Xiao Zhou,* Xiaoxiao He* and Kemin Wang*, "In situ multiplex detection of serum exosomal microRNAs using an all-in-one biosensor for breast cancer diagnosis", Analyst, 2020, 145(9): 3289-3296. DOI:10.1039/d0an00393j.

Jinqing Gu, Zhenzhen Qiao,  Xiaoxiao He, Yanru Yu, Yanli Lei, Jinlu Tang, Hui Shi,* Dinggeng He* and Kemin Wang, "Enzyme-free amplified detection of miRNA based on target-catalyzed hairpin assembly and DNA-stabilized fluorescent silver nanoclusters", Analyst, 2020, 145(15): 5194-5199. DOI:10.1039/d0an00545b.

Min Hou, Dinggeng He,* Hongchang Bu, Huizhen Wang, Jin Huang, Jinqing Gu, Ri Wu, Hung-Wing Li, Xiaoxiao He* and Kemin Wang*, "A sandwich-type surface-enhanced Raman scattering sensor using dual aptamers and gold nanoparticles for the detection of tumor extracellular vesicles", Analyst, 2020, 145(19): 6232-6236. DOI:10.1039/d0an01385d.

Shaoyuan Li, Yan Zheng, Yaqin Liu, Xiuhua Geng, Xiaofeng Liu, Liyuan Zou, Qing Wang, Xiaohai Yang, Kemin Wang, "Investigation of the interaction between split aptamer and vascular endothelial growth factor 165 using single molecule force spectroscopy", Journal of Molecular Recognition, 2020, 33(5): e2829. DOI:10.1002/jmr.2829.

Jin Huang, Wenjie Ma, Huanhuan Sun, Huizhen Wang, Xiaoxiao He,* Hong Cheng, Mingmin Huang,* Yanli Lei, and Kemin Wang, "Self-assembled DNA nanostructures-based nanocarriers enabled functional nucleic acids delivery", ACS Applied Bio Materials, 2020, 3(5): 2779-2795. DOI:10.1021/acsabm.9b01197.

Yan Zheng, Pei Wang, Shaoyuan Li, Xiuhua Geng, Liyuan Zou, Meimei Jin, Qingqing Zou, Qing Wang,* Xiaohai Yang,* and Kemin Wang, "Development of DNA aptamer as a β-amyloid aggregation inhibitor", ACS Applied Bio Materials, 2020, DOI: 10.1021/acsabm.0c00996.

Yanjing Yang, Yao He, Zhiwei Deng, Jiacheng Li, Xiufang Li, Jin Huang*, Shian Zhong*, "An autonomous self-cleavage DNAzyme walker for live cell microRNA imaging", ACS Applied Bio Materials, 2020, 3: 6310-6318. DOI:10.1021/acsabm.0c00777.

Luo Hai, Anman Zhang, Xu Wu, Hong Cheng, Dinggeng He,* Tianzheng Wang, Xiaoxiao He,* and Kemin Wang*, "Liposome-stabilized black phosphorus for photothermal drug delivery and oxygen self-enriched photodynamic therapy", ACS Applied Nano Materials, 2019, 3(1): 563-575. DOI:10.1021/acsanm.9b02119.

Qiaoshu Chen, Meiling Jian, Hui Chen, Bing Zhou, Hui Shi, Xiaohai Yang, Kemin Wang, and Jianbo Liu*. Design of lipophilic split aptamers as artificial carriers for transmembrane transport of adenosine triphosphate. CCS Chemistry, 2020. DOI:10.31635/ccschem.020.202000591.

Yingben Wu,* Yan Liu (co-author), Huizhi Liu, Biao Liu, Wei Chen, Lijuan Xu and Jianbo Liu.* Ion-mediated self-assembly of Cys-capped quantum dots for fluorescence detection of As(III) in water. Analytical Methods, 2020, 12, 4229-4234. DOI:10.1039/d0ay01144d.

Qiaoshu Chen, Yibo Liu, Jianbo Liu,* Juewen Liu.* Liposome boosted peroxidase mimicking nanozymes breaking the pH limit. Chemistry - A European Journal, 2020, 26, 16659-16665. DOI:10.1002/chem.202004133.

2019

Nuli Xie†, Shiyuan Liu†, Hongmei Fang, Yanjing Yang, Ke Quan, Jing Li, Xiaohai Yang, Kemin Wang, and Jin Huang*, Three-Dimensional molecular transfer from DNA Nanocages to Inner Gold Nanoparticle Surfaces, ACS Nano, 13(4), 4174−4182(2019). DOI: 10.1021/acsnano.8b09147 

Huanhuan Sun, Taiping Qing, Xiaoxiao He*, Jingfang Shangguan, Ruichen Jia, Hongchang Bu, Jin Huang, Kemin Wang*, Rapid synthesis of Au/Ag bimetallic nanoclusters with highly biochemical stability and its applications for temperature and ratiometric pH sensing, Analytica chimica acta, 1070, 88-96(2019). DOI: 10.1016/j.aca.2019.04.029

Wenjie Ma, Biao Chen, Shanzi Zou, Ruichen Jia, Hong Cheng, Jin Huang, Huizhen Wang, Xiaoxiao He* and Kemin Wang*. I-motif-based in situ bipedal hybridization chain reaction for specific activatable imaging and enhanced delivery of antisense oligonucleotides, Analytical Chemistry, 91(19), 12538-12545(2019). DOI: 10.1021/acs.analchem.9b03420

Ruichen Jia, Xiaoxiao He*, Wenjie Ma, Yanli Lei, Hong Cheng, Huanhuan Sun, Jin Huang, Kemin Wang*, Aptamer-Functionalized Activatable DNA Tetrahedron Nanoprobe for PIWI-Interacting RNA Imaging and Regulating in Cancer Cells, Analytical Chemistry, 91(23), 15107-15113(2019). DOI: 10.1021/acs.analchem.9b03819 

Hong Cheng, Wei Li, Shuangdi Duan, Jiaxin Peng, Jinquan Liu, Wenjie Ma, Huizhen Wang, Xiaoxiao He,* and Kemin Wang*, Mesoporous Silica Containers and Programmed Catalytic Hairpin Assembly/Hybridization Chain Reaction Based Electrochemical Sensing Platform for MicroRNA Ultrasensitive Detection with Low Background, Analytical Chemistry, 91(16), 10672-10678(2019). DOI: 10.1021/acs.analchem.9b01947 

Yan Yuan,Yanyun Ma, Lei, Luo, Qing Wang, Jin Huang, Jianbo Liu, Xiaohai Yang*, Kemin Wang*, Ratiometric determination of human papillomavirus-16 DNA by using fluorescent DNA-templated silver nanoclusters and hairpin-blocked DNAzyme-assisted cascade amplification, Microchimica Acta, 186(9), UNSP 613(2019). DOI: 10.1007/s00604-019-3732-y

Xiaohong Wen†, Baoyin Yuan†, Junxun Zhang, Xiangxian Meng, Qiuping Guo,* Lie Li, Zenghui Li, Huishan Jiang and Kemin Wang*, Enhanced visualization of cell surface glycans via a hybridization chain reaction, Chemical Communications, 55 (43), 6114-6117(2019). DOI: 10.1039/c9cc02069a 

Haifeng Li , Yu Yao , Hui Shi , Yanli Lei , Yan Huang , Kemin Wang , Xiaoxiao He* and Jianbo Liu*, A near-infrared light-responsive nanocomposite for photothermal release of H2S and suppression of cell viability, Journal of Materials Chemistry B, 7(39), 5992-5997(2019). DOI: 10.1039/c9tb01611b 

Qiaoshu Chen, Shaohong Zhou, Chunying Li, Qiuping Guo, Xiaohai Yang, Jin Huang, Jianbo Liu* and Kemin Wang*, DNA supersandwich assemblies as artificial receptors to mediate intracellular delivery of catalase for efficient ROS scavenging, Chemical Communications, 55(29), 4242-4245(2019). DOI: 10.1039/c9cc00201d

Xiaofeng Liu1, Hua Zhang1, Shiya Qin, Qing Wang, Xiaohai Yang, Kemin Wang*, Optical fiber amplifier for quantitative and sensitive point-of-care testing of myoglobin and miRNA-141, Biosensors and Bioelectronics, 129, 87-92(2019). DOI: 10.1016/j.bios.2018.12.056 

Qing Wang, Liyuan Zou, Xiaohai Yang∗, Xiaofeng Liu, Wenyan Nie, Yan Zheng, Quan Cheng, Kemin Wang*, Direct quantification of cancerous exosomes via surface plasmon resonance with dual gold nanoparticle-assisted signal amplification, Biosensors and Bioelectronics, 135, 129-136(2019). DOI: 10.1016/j.bios.2019.04.013 

Xiaofeng Liu, Guofu Liao, Liyuan Zou, Yan Zheng, Xiaohai Yang, Qing Wang,* Xiuhua Geng, Shaoyuan Li, Yaqin Liu, and Kemin Wang*, Construction of Bio/Nanointerfaces: Stable Gold Nanoparticle Bioconjugates in Complex Systems, ACS Applied Materials and Interfaces, 11(43), 40817-40825(2019). DOI: 10.1021/acsami.9b13659 

Xiaofeng Liu, Liyuan Zou, Xiaohai Yang, Qing Wang*, Yan Zheng, Xiuhua Geng, Guofu Liao, Wenyan Nie, and Kemin Wang*, Point-of-Care Assay of Alkaline Phosphatase Enzymatic Activity Using a Thermometer or Temperature Discoloration Sticker as Readout, Analytical Chemistry, 91(12), 7943-7949(2019). DOI: 10.1021/acs.analchem.9b01883 

Jin Huang, Jingfang Shangguan, Qiuping Guo, Wenjie Ma, Huizhen Wang, Ruichen Jia, Zi Ye, Xiaoxiao He*,  and Kemin Wang*, Colorimetric and fluorescent dual-mode detection of microRNA based on duplex-specific nuclease assisted gold nanoparticle amplification, Analyst, 144(16), 4917-4924(2019). DOI: 10.1039/c9an01013k 

Yan Zheng, Qing Wang,* Xiaohai Yang, Wenyan Nie, Liyuan Zou, Xiaofeng Liu, and Kemin Wang*, Aptamer as a Tool for Investigating the Effects of Electric Field on Aβ40 Monomer and Aggregates Using Single-Molecule Force Spectroscopy, Analytical Chemistry, 91(3), 1954-1961(2019). DOI: 10.1021/acs.analchem.8b04278 

Dinggeng He, See-Lok Ho, Hei-Nga Chan, Huizhen Wang, Luo Hai, Xiaoxiao He,*, Kemin Wang,*and Hung-Wing Li*, Molecular-Recognition-Based DNA Nanodevices for Enhancing the Direct Visualization and Quantification of Single Vesicles of Tumor Exosomes in Plasma Microsamples, Analytical Chemistry 91 (4): 2768-2775(2019). DOI: 10.1021/acs.analchem.8b04509 

Hui Shi†, Yanli Lei†, Jia Ge,Xiaoxiao He,Wensi Cui,Xiaosheng Ye,Jianbo Liu,and Kemin Wang*, A Simple, pH-Activatable Fluorescent Aptamer Probe with Ultralow Background for Bispecific Tumor Imaging, Analytical Chemistry, 91(14), 9154-9160(2019). DOI: 10.1021/acs.analchem.9b01828 

Yanjing Yang, Shian Zhong, Kemin Wang and Jin Huang*, Gold nanoparticle based fluorescent oligonucleotide probes for imaging and therapy in living systems, Analyst, 144(4), 1052-1072(2019). DOI: 10.1039/c8an02070a 

Xiaosheng Ye, Xiaoxiao He, Yanli Lei, Jinlu Tang, Yanru Yu, Hui Shi*and Kemin Wang*, One-pot synthesized Cu/Au/Pt trimetallic nanoparticles with enhanced catalytic and plasmonic properties as a universal platform for biosensing and cancer theranostics, Chemical Communications, 55(16), 2321-2324(2019). DOI: 10.1039/c8cc10127b

Chunying Li, Hui Chen, Li Zhou, Hui Shi, Xiaoxiao He, Xiaohai Yang*,Kemin Wang and Jianbo Liu*, Single-stranded DNA designed lipophilic G-quadruplexes as transmembrane channels for switchable potassium transport, Chemical Communications, 55(80), 12004-12007(2019). DOI: 10.1039/c9cc04176a

Lin Lan, Qiuping Guo, Hemin Nie, Chang Zhou, Qingyun Cai,Jin Huang* and Xiangxian Meng*, a Linear-hairpin variable primer RT-qPCR for MicroRNA, Chemical Science, 10(7), 2034-2043(2019). DOI: 10.1039/c8sc04621b 

Yujie Zhao, Wenjie Ma, Shanzi Zou, Biao Chen, Hong Cheng, Xiaoxiao He*, Kemin Wang*, Terminal deoxynucleotidyl transferase-initiated molecule beacons arrayed aptamer probe for sensitive detection of metastatic colorectal cancer cells, Talanta, 202, 152-158(2019). DOI: 10.1016/j.talanta.2019.04.065 

Miaomiao Zhuang, Yanwen Zhang, Shaohong Zhou, Yun Zhang, Kemin Wang, Jinfang Nie* and Jianbo Liu*, Uricase-containing coacervate microdroplets as enzyme active membrane-free protocells for detoxification of uric acid in serum, Chemical Communication, 55, 13880-13883(2019). DOI: 10.1039/c9cc07037k 

Ke Quan, Cuiping Yi, Xiaohai Yang, Xiaoxiao He, Jin Huang*, Kemin Wang*, FRET-based Nucleic Acid Probes: Basic Designs and Applications in Bioimaging, Trends in Analytical Chemistry, 2019. DOI: 10.1016/j.trac.2019.115784

2018

Huizhen Wang, Dinggeng He,* Ri Wu, Hong Cheng, Wenjie Ma, Jin Huang,Hongchang Bu, Xiaoxiao He* and Kemin Wang, A hybridization-triggered DNAzyme cascade assay for enzyme-free amplified fluorescence detection of nucleic acids, Analyst, 144(1), 143-147(2018). DOI: 10.1039/c8an01796d 

Ke Quan, Jing Li, Jiaoli Wang, Nuli Xie, Qiaomei Wei, Jinlu Tang, Xiaohai Yang, Kemin Wang and Jin Huang*, Dual-microRNA-controlled double-amplified cascaded logic DNA circuits for accurate discrimination of cell subtypes, Chemical Science, 10(5), 1442–1449(2018). DOI: 10.1039/c8sc04887h 

Fengzhou Xu†, Lan Luo†, Hui Shi*, Xiaoxiao He, Yanli Lei, Jinlu Tang, Dinggeng He, Zhenzhen Qiao and Kemin Wang*, Label-free and sensitive microRNA detection based on a target recycling amplification-integrated superlong poly(thymine)-hosted copper nanoparticle strategy, Analytica Chimica Acta, 2018, 1010, 54-61. DOI: doi.org/10.1016/j.aca.2018.01.010.

Yan Zheng, Qing Wang*, Xiaohai Yang, Wenyan Nie, Liyuan Zou, Xiaofeng Liu, and Kemin Wang*, “Aptamer as a Tool for Investigating the Effects of Electric Field on Aβ40 Monomer and Aggregates Using Single Molecule Force Spectroscopy”, Analytical Chemistry. DOI: 10.1021/acs.analchem.8b04278 (2018)

Hongmei Fang†, Nuli Xie†, Min Ou, Jin Huang, Wenshan Li, Qing Wang, Jianbo Liu, Xiaohai Yang*, and Kemin Wang*, Detection of Nucleic Acids in Complex Samples via Magnetic Microbead-Assisted Catalyzed Hairpin Assembly and “DD–A” FRET,Analytical Chemistry 90 (12), 7164-7170 (2018). DOI: 10.1021/acs.analchem.8b01330    

Baoyin Yuan, Yuanyuan Chen, Yuqiong Sun, Qiuping Guo*, Jin Huang, Jianbo Liu, Xiangxian Meng, Xiaohai Yang, Xiaohong Wen, Zenghui Li, Lie Li, and Kemin Wang*, Enhanced Imaging of Specific Cell-Surface Glycosylation Based on Multi-FRET,Analytical Chemistry 90 (10), 6131-6137 (2018). DOI: 10.1021/acs.analchem.8b00424

Wenjie Ma, Lv’an Yan, Xiaoxiao He*, Taiping Qing, Yanli Lei, Zhenzhen Qiao, Dinggeng He, Kaihang Huang, Kemin Wang*, Hairpin-Contained i-Motif Based Fluorescent Ratiometric Probe for High-Resolution and Sensitive Response of Small pH Variations, Analytical Chemistry, 2018, 90(3), 1889-1896.DOI: 10.1021/acs.analchem.7b03972    

Hong Cheng, Jinquan Liu, Wenjie Ma, Shuangdi Duan, Jin Huang, Xiaoxiao He*, and Kemin Wang*, Low Background Cascade Signal Amplification Electrochemical Sensing Platform for Tumor-Related mRNA Quantification by Target-Activated Hybridization Chain Reaction and Electroactive Cargo Release, Analytical Chemistry 90 (21), 12544-12552 (2018). DOI:10.1021/acs.analchem.8b02470    

Wenyan Nie, Qing Wang*, Liyuan Zou, Yan Zheng, Xiaofeng Liu, Xiaohai Yang, and Kemin Wang*, Low-Fouling Surface Plasmon Resonance Sensor for Highly Sensitive Detection of MicroRNA in a Complex Matrix Based on the DNA Tetrahedron, Analytical Chemistry 90 (21), 12584-12591 (2018).DOI: 10.1021/acs.analchem.8b02686    

Xiaofeng Liu‡, Hua Zhang‡, Shiya Qin, Qing Wang*, Xiaohai Yang, Kemin Wang*, Optical fiber amplifier for quantitative and sensitive point-of-care testing of myoglobin and miRNA-141, Biosensors and Bioelectronics, 2018, Ms. Ref. No.: BIOS-D-18-03867R1    

Duo Li†, Zhenzhen Qiao†, Yanru Yu, Jinlu Tang, Xiaoxiao He, Hui Shi*, Xiaosheng Ye, Yanli Lei and Kemin Wang*. In situ fluorescence activation of DNA-silver nanoclusters as a label-free and general strategy for cell nucleus imaging, Chemical Communication, 2018, 54(9), 1089-1092. DOI: 10.1039/c7cc08228b

Yanli Lei, Xiaoxiao He, Jinlu Tang, Hui Shi*, Dinggeng He, Lv An Yan, Jianbo Liu, Yu Zeng, and Kemin Wang*, Ultra-pH-responsive split i-motif based aptamer anchoring strategy for specific activatable imaging of acidic tumor microenvironment, Chemical Communications 54 (73), 10288-10291 (2018). DOI: 10.1039/c8cc04420a

Jiaoli Wang, Jin Huang*, Ke Quan, Jing Li, Yanan Wu, Qiaomei Wei, Xiaohai Yang, and Kemin Wang*, Hairpin-fuelled catalytic nanobeacons for amplified microRNA imaging in live cells, Chemical Communications 54 (73), 10336-10339 (2018). DOI: 10.1039/c8cc06298f

Qiaomei Wei, Jin Huang*, Jing Li, Jiaoli Wang, Xiaohai Yang, Jianbo Liu, and Kemin Wang*, A DNA nanowire based localized catalytic hairpin assembly reaction for microRNA imaging in live cells, Chemical Science 9 (40), 7802-7808 (2018).DOI: 10.1039/C8SC02943A

Ke Quan, Jing Li, Jiaoli Wang, Nuli Xie, Qiaomei Wei, Jinlu Tang, Xiaohai Yang, Kemin Wang, and Jin Huang*, Dual-MicroRNA-Controlled Double-Amplified Cascaded Logic DNA Circuits for Cell Subtypes Accurate Discrimination, Chemical Science DOI: 10.1039/C8SC04887H (2019).

Lin Lan, Qiuping Guo, Hemin Nie, Chang Zhou, Qingyun Cai, Jin Huang* and Xiangxian Meng*, Linear-hairpin variable primer RT-qPCR for MicroRNA, Chemical Science DOI: 10.1039/c8sc04621b, (2019).

Li Li†, Gui Li†, Xiaoxiao He, Xiaohai Yang, Songyang Liu, Jinlu Tang, Qiaoshu Chen, Jianbo Liu*, and Kemin Wang*, Protein- driven disassembly of surfactant- polyelectrolyte nanomicelles: Modulation of quantum dot/fluorochrome FRET for pattern sensing, Sensors and Actuators B: Chemical 272, 393-399 (2018).DOI: doi.org/10.1016/j.snb.2018.05.130

Yanli Lei, Zhenzhen Qiao, Jinlu Tang, Xiaoxiao He, Hui Shi*, Xiaosheng Ye, Lv'an Yan, Dinggeng He, and Kemin Wang*, DNA nanotriangle-scaffolded activatable aptamer probe with ultralow background and robust stability for cancer theranostics, Theranostics 8 (15), 4062-4071 (2018).DOI: 10.7150/thno.24683

2016

1 

Le Ying, Nuli Xie,  Yanjing Yang, Xiaohai Yang, Qifeng Zhou, Bincheng Yin, Jin Huang,*  and Kemin Wang*.A cell-surface-anchored ratiometric i-motif sensor for extracellular pH detection,Chem. Commun. 2016, 52, 7818-7821 . DOI: 10.1039/C6CC03163C 

2 

Jin Huang, He Wang, Xiaohai Yang, Yanjing Yang, Ke Quan, Le Ying, Nuli Xie, Min Ou, and Kemin Wang,Fluorescence resonance energy transfer-based hybridization chain reaction for in situvisualization of tumor-related mRNA,Chem. Sci. 2016, 7, 3829-3835. DOI: 10.1039/C6SC00377J 

3 

Nandi Chen,  Xiaohai Yang,*  Qing Wang, Lixin Jian, Hui Shi, Shiya Qin, Kemin Wang,* Jin Huang  and Wenjing Liu.  Proof of concept for inhibiting metastasis: circulating tumor cell-triggered localized release of anticancer agent via a structure-switching aptamerChem. Commun., 2016, 52, 6789-6792. DOI: 10.1039/C6CC02374F 

4 

Baoyin Yuan, Yu Zhou, Qiuping Guo,* Kemin Wang,* Xiaohai Yang, Xiangxian Meng, Jun Wan, Yuyu Tan, Zhixiang Huang, Qin Xie and Xiayu Zhao. A signal-on split aptasensor for highly sensitive and specific detection of tumor cells based on FRET. Chem. Commun., 2016, 52, 1590-1593. DOI: 10.1039/C5CC08060F 

5 

Nuli Xie, Jin Huang*,  Xiaohai Yang, Yanjing Yang, Ke Quan, He Wang, Le Ying, Min Ou, and Kemin Wang*,  A DNA tetrahedron-based molecular beacon for tumor-related mRNA detection in living cells,  Chem. Commun. 2016, 52, 2346-2349. DOI: 10.1039/C5CC09980C 

6 

Jin Huang, He Wang, Xiaohai Yang, Yanjing Yang, Ke Quan, Le Ying, Nuli Xie, Min Ou, and Kemin Wang,A supersandwich fluorescence in situ hybridization strategy for highly sensitive and selective mRNA imaging in tumor cells,Chem. Commun. 2016, 52(2), 370-373. DOI:10.1039/c5cc08503a 

7 

Jinlu Tang, Hui Shi, Xiaoxiao He, Yanli Lei, Qiuping Guo, Kemin Wang*, Lv’an Yan and Dinggeng He. Tumor cell-specific split aptamers: target-driven and temperature-controlled self-assembly on the living cell surface. Chem. Commun., 2016, 52:1482–1485. DOI: 10.1039/C5CC08977H 

8 

Xiaosheng Ye, Hui Shi, Xiaoxiao He*, Yanru Yu, Dinggeng He, Jinlu Tang, Yanli Lei,  and Kemin Wang*. Cu–Au alloy nanostructures coated with aptamers: a simple, stable and highly effective platform for in vivo cancer theranosticsNanoscale, 2016, 8:2260–2267. DOI: 10.1039/C5NR07017A 

9 

Qing Wang, Rongjuan Liu, Xiaohai Yang,*  Kemin Wang,* Jinqing Zhu, Leiliang He and Qing Li. Surface plasmon resonance biosensor for enzyme-free amplified microRNA detection based on gold nanoparticles and DNA supersandwich. Sensors and Actuators B: Chemical, 2016, 223: 613-620. DOI: 10.1016/j.snb.2015.09.152 

10 

Bin Wu, Rui Jiang, Qing Wang, Jin Huang, Xiaohai Yang,*  Kemin Wang*, Wenshan Li, Nandi Chen and Qing Li.  Detection of C-reactive protein using nanoparticle-enhanced surface plasmon resonance using an aptamer-antibody sandwich assayChem. Commun., 2016,52, 3568-3571. DOI: 10.1039/C5CC10486F 

11 

Wenjin Liu, Min Lin, Xiaohai Yang,* Bin Wu, Nandi Chen, Qing Wang, Kemin Wang* and Shiya Qin.  Investigation of newly identified G-quadruplexes and their application to DNA detection. Analyst, 2016,141, 4463-4469. DOI: 10.1039/C6AN00987E 

12 

Xi Guo , Yanwen Zhang, Jianbo Liu,* Xiaohai Yang , Jin Huang, Li Li, Lan Wan and Kemin Wang *. Red blood cell membrane-mediated fusion of hydrophobic quantum dots with living cell membranes for cell imaging. J. Mater. Chem. B, 2016, 4, 4191-4197 DOI: 10.1039/C6TB01067A 

2015

1 

Jun Wan, Ling Ye, Xiaohai Yang, Qiuping Guo, Kemin Wang, Zhixiang Huang, Yuyu Tan, Baoyin Yuan, and Qin Xie, Cell-SELEX based selection and optimization of DNA aptamers for specific recognition of human cholangiocarcinoma QBC-939 cells, ANALYST 140 (17), 5992-5997 (2015).  DOI:10.1039/c5an01055a 

2 

Jin Huang, Le Ying, Xiaohai Yang, Yanjing Yang, Ke Quan, He Wang, Nuli Xie, Min Ou, Qifeng Zhou, and Kemin Wang,Ratiometric Fluorescent Sensing of pH Values in Living Cells by Dual-Fluorophore-Labeled i-Motif Nanoprobes, ANAL CHEM 87 (17), 8724-8731 (2015).DOI: 10.1021/acs.analchem.5b01527 

3 

Qing Wang, Qing Li, Xiaohai Yang, Kemin Wang, Shasha Du, Hua Zhang, and Yajie Nie, Graphene oxide–gold nanoparticles hybrids-based surface plasmon resonance for sensitive detection of microRNA, Biosensors and Bioelectronics 77, 1001-1007 (2016). doi:10.1016/j.bios.2015.10.091 

4 

Zhen Zou, Xiaoxiao He, Dinggeng He, *Kemin Wang, Zhihe Qing, Xue Yang, Li Wen, Jun Xiong, Liling Li, Linli Cai. Programmed packaging of mesoporous silica nanocarriers for matrix metalloprotease 2-triggered tumor targeting and releaseBiomaterials2015, 58: 35-45. DOI: 10.1016/j.biomaterials.2015.04.034.

5 

Yanjing Yang, Jin Huang, Xiaohai Yang, Ke Quan, He Wang, Le Ying , Nuli Xie, Min Ou, and Kemin Wang*. FRET Nanoflares for Intracellular mRNA Detection: Avoiding False Positive Signals and Minimizing Effects of System FluctuationsJournal of the American Chemical Society2015, 137 (26): 8340–8343. DOI: 10.1021/jacs.5b04007. 

6 

Jingfang Shangguan, Yuhong Li, Dinggeng He,  Xiaoxiao He*,  Kemin Wang*, Zhen Zou and Hui Shi. A combination of positive dielectrophoresis driven on-line enrichment and aptamer-fluorescent silica nanoparticle label for rapid and sensitive detection of Staphylococcus aureus. Analyst2015, 140: 4497. DOI: 10.1039/C5AN00535C.

7 

Xiaosheng Ye, Hui Shi, Xiaoxiao He*, Kemin Wang*, Dinggeng He, Lv’an Yan, Fengzhou Xu, Yanli Lei, Jinlu Tang, and Yanru Yu. Iodide-Responsive Cu–Au Nanoparticle-Based Colorimetric Platform for Ultrasensitive Detection of Target Cancer CellsAnalytical Chemistry, 2015, 87 (14):7141–7147. DOI: 10.1021/acs.analchem.5b00943.  

8 

Zhengui Mao, Zhihe Qing, Taiping Qing, Fengzhou Xu, Li Wen, Xiaoxiao He*, Dinggeng He, Hui Shi, and Kemin Wang*. Poly(thymine)-Templated Copper Nanoparticles as a Fluorescent Indicator for Hydrogen Peroxide and Oxidase-Based BiosensingAnalytical Chemistry2015, 87 (14): 7454–7460. DOI: 10.1021/acs.analchem.5b01700.

9 

Qing Wang, Xiaohan Yang, Xiaohai Yang,  Pei Liu, Kemin Wang*, Jin Huang, Jianbo Liu, Chunxia Song and Jingjing Wang. Colorimetric detection of mercury ion based on unmodified gold nanoparticles and target-triggered hybridization chain reaction amplificationSpectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy2015, 136: 283-287. doi:10.1016/j.saa.2014.08.129 

10 

Xiaochen Guo, Xiaohai Yang*, Pei Liu, Kemin Wang*, Qing Wang, Qiuping Guo, Jin Huang, Wenshan Li, Fengzhou Xu and Chunxia Song. Multiple amplification detection of microRNA based on the host–guest interaction between β-cyclodextrin polymer and pyreneAnalyst, 2015,140, 4291-4297. DOI: 10.1039/C5AN00626K 

11 

Jinquan Liu, Xiaoxiao He, Kemin Wang, Dinggeng He, Yonghong Wang, Yinfei Mao, Hui Shi, Li Wen. A highly sensitive electrochemiluminescence assay for protein kinase based on double-quenching of graphene quantum dots by G-quadruplex–hemin and gold nanoparticles. Biosensors and Bioelectronics2015, 70: 54-60. DOI:10.1016/j.bios.2015.03.026.

12 

Meng Yang , Xiaohai Yang*, Kemin Wang*, Qing Wang, Xin Fan, Wei Liu, Xizhen Liu, Jianbo Liu, and Jin Huang. Tuning Transport Selectivity of Ionic Species by Phosphoric Acid Gradient in Positively Charged Nanochannel MembranesAnalytical chemistry2015, 87(3): 1544-1551. DOI: 10.1021/ac503813r 

13 

Leiliang He, Xiaohai Yang*, Fang Zhao , Kemin Wang*, Qing Wang, Jianbo Liu, Jin Huang, Wenshan Li, and Meng Yang. Self-Assembled Supramolecular Nanoprobes for Ratiometric Fluorescence Measurement of Intracellular pH ValuesAnalytical chemistry2015, 87(4): 2459-2465. DOI: 10.1021/ac504458r.

14 

Pei Liu, Shan Sun, Xiaochen Guo, Xiaohai Yang*, Jin Huang, Kemin Wang*, Qing Wang, Jianbo Liu, and Leiliang He. Competitive Host–Guest Interaction between β-Cyclodextrin Polymer and Pyrene-Labeled Probes for Fluorescence AnalysesAnalytical Chemistry2015, 87 (5): 2665–2671. DOI: 10.1021/ac503301q. 

15 

Fengzhou Xu, Hui Shi, Xiaoxiao He,  Kemin Wang*, Dinggeng He,  Lv'an Yan, Xiaosheng Ye, Jinlu Tang, Jingfang Shangguan and Lan Luo. Masking agent-free and channel-switch-mode simultaneous sensing of Fe3+ and Hg2+ using dual-excitation graphene quantum dotsAnalyst2015,140: 3925-3928. DOI: 10.1039/C5AN00468C.

16 

Jianbo Liu , Gui Li , Xiaohai Yang , Kemin Wang *, Li Li , Wei Liu , Xing Shi , and Yali Guo. Exciton Energy Transfer-Based Quantum Dot Fluorescence Sensing Array:“Chemical Noses” for Discrimination of Different NucleobasesAnalytical chemistry2015, 87(2), pp 876–883. DOI: 10.1021/ac503819e 

17 

Qing Wang, Lin Liu, Xiaohai Yang,*Kemin Wang,*Nandi Chen, Chenchen Zhou, Bianxia Luo, and Shasha Du. Evaluation of Medicine Effects on the Interaction of Myoglobin and its Aptamer or Antibody Using Atomic Force Micros-copyAnalytical Chemistry2015, 87 (4), pp, 2242–2248. DOI: 10.1021/ac503885e 

18 

 Min Lin, Wenshan Li, Yaning Wang, Xiaohai Yang,* Kemin Wang,* Qing Wang, Pei Wang, Yujie Chang, Yuyu Tan. Discrimination of hemoglobins with subtle differences using an aptamer based sensing array. Chemical Communications2015DOI: 10.1039/C5CC00929D 

19 

 Qing Wang, Fang Liu, Xiaohai Yang, Kemin Wang*, Hui Wang and Xin Deng. Sensitive Point-Of-Care Monitoring of Cardiac Biomarker Myoglobin Using Aptamer and Ubiquitous Personal Glucose MeterBiosensors and Bioelectronics2015, 64(0): 161-64. DOI: 10.1016/j.bios.2014.08.079 

20 

 Wei Liu, Jianbo Liu, Xiaohai Yang, Kemin Wang*, Qing Wang, Meng Yang, Li Li and Chunxia Song. Phosphate Modulated Permeability of Mesoporous Silica Spheres: A Biomimetic Ion Channel Decorated Compartment ModelJournal of Materials Chemistry B2015, 3(2): 323-29. DOI:  10.1039/C4TB01532K 

21 

Ke Quan, Jin Huang, Xiaohai Yang,Yanjing Yang, Le Ying, He Wang, Yong He and Kemin Wang*. An Enzyme-Free and Amplified Colorimetric Detection Strategy via Target-Aptamer Binding Triggered Catalyzed Hairpin AssemblyChemical Communications2015, 51(5): 937-940. DOI:  10.1039/C4CC08488H 

22 

Chunxia Song, Xiaohai Yang, Kemin Wang*, Qing Wang, Jianbo Liu, Jin Huang, Leiliang He, Pei Liu, Zhihe Qing and Wei Liu. Sensitive Detection of T4 Polynucleotide Kinase Activity Based On β-Cyclodextrin Polymer Enhanced Fluorescence Combined with Exonuclease ReactionChemical Communications,2015, 51(10): 1815-1818. DOI: 10.1039/C4CC08991J 

23 

Dinggeng He, Xiaoxiao He, Kemin Wang*, Xue Yang, Yang, Xiaoxiao, Zhen Zou and Xuecai Li. Redox-Responsive Degradable Honeycomb Manganese Oxide Nanostructures as Effective Nanocarriers for Intracellular Glutathione-Triggered Drug ReleaseChemical Communications2015, 51(4): 776-779. DOI: 10.1039/C4CC08172B 

2014

1 

 Yuyu Tan, Qiuping Guo, Xiayu Zhao, Xiaohai Yang, Kemin Wang*, Jin Huang, Yu Zhou. Proximity-dependent protein detection based on enzyme assisted fluorescence signal amplificationBiosensorsandBioelectronics2014, 51: 255–260. DOI: 10.1016/j.bios.2013.08.001 

2 

Yuyu Tan, Qiuping Guo, Qin Xie, Kemin Wang*, Baoyin Yuan, Yu Zhou, Jianbo Liu, Jin Huang, Xiaoxiao He, Xiaohai Yang, Chunmei He and Xiayu Zhao. Single-Walled Carbon Nanotubes (SWCNTs)-Assisted Cell-Systematic Evolution of Ligands by Exponential Enrichment (Cell-SELEX) for Improving Screening EfficiencyAnalytical Chemistry2014, 86(19): 9466-72. DOI: 10.1021/ac502166b 

3 

 Zhihe Qing, Zhengui Mao, Taiping Qing, Xiaoxiao He, Zhen Zou, Dinggeng He, Hui Shi, Jin Huang, Jianbo Liu and Kemin Wang*. Visual and Portable Strategy for Copper(II) Detection Based on a Striplike Poly(Thymine)-Caged and Microwell-Printed HydrogelAnalytical Chemistry2014, 86(22): 11263-68. DOI: 10.1021/ac502843t 

4 

 LvAn Yan, Hui Shi, Xiaoxiao He, Kemin Wang*, Jinlu Tang, Mian Chen, Xiaosheng Ye, Fengzhou Xu and Yanli Lei. A Versatile Activatable Fluorescence Probing Platform for Cancer Cells in Vitro and In Vivo Based on Self-Assembled Aptamer/Carbon Nanotube Ensembles. Analytical Chemistry2014, 86(18): 9271-77. DOI: 10.1021/ac5024149 

5 

 Fengzhou Xu, Hui Shi, Xiaoxiao He, Kemin Wang*, Dinggeng He, Qiuping Guo, Zhihe Qing, Lv’an Yan, Xiaosheng Ye, Duo Li, and Jinlu Tang. Concatemeric dsDNA-Templated Copper Nanoparticles Strategy with Improved Sensitivity and Stability Based on Rolling Circle Replication and Its Application in MicroRNA DetectionAnalytical Chemistry2014, 86, 6976−6982. DOI: 10.1021/ac500955r 

6 

Qing Wang, Wei Liu, Yuqian Xing, Xiaohai Yang*, Kemin Wang*, Rui Jiang, Pei Wang and Qing Zhao. Screening of DNA Aptamers against Myoglobin Using a Positive and Negative Selection Units Integrated Microfluidic Chip and Its Biosensing Application. Analytical Chemistry2014, 86, 6572-6579. DOI: 10.1021/ac501088q 

7 

 Zhihe Qing, Xiaoxiao He*, Jin Huang, Kemin Wang*, Zhen Zou, Taiping Qing, Zhengui Mao, Hui Shi and Dinggeng He. Target-Catalyzed Dynamic Assembly-Based Pyrene Excimer Switching for Enzyme-Free Nucleic Acid Amplified Detection. Analytical Chemistry2014, 86, 4934-4939. DOI: 10.1021/ac500834g 

8 

 Mian Chen, Xiaoxiao He, Kemin Wang*, Dinggeng He, Xiaohai Yang, Hui Shi. Inorganic fluorescent nanoprobes for cellular and subcellular imagingTrends in Analytical Chemistry2014, 58: 120-129. DOI: 10.1016/j.trac.2014.03.003 

9 

 Mian Chen, Xiaoxiao He, Kemin Wang*, Dinggeng He, Shuna Yang, Pengchao Qiu and Suye Chen. A pH-responsive Polymer/Mesoporous Silica Nano-Container Linked through an Acid Cleavable Linker for Intracellular Controlled Release and Tumor Therapy In VivoJournal of Materials Chemistry B, 2014, 2(4): 428-36. DOI:  10.1039/C3TB21268H 

10 

 Mian Chen, Pengchao Qiu, Xiaoxiao He, Kemin Wang*, Suye Chen, Shuna Yang and Xiaosheng Ye. The Adenine DNA Self-Assembly of pH- and Near-Infrared-Responsive Gold Nanorod Vehicles for the Chemothermal Treatment of Cancer CellsJournal of Materials Chemistry B2014, 2(21): 3204-13. DOI:  10.1039/C4TB00103F 

11 

 Mian Chen, Shuna Yang, Xiaoxiao He, Kemin Wang*, Pengchao Qiu and Dinggeng He. Co-Loading of Coralyne and Indocyanine Green Into Adenine DNA-functionalized Mesoporous Silica Nanoparticles for pH- and Near-Infrared-Responsive Chemothermal Treatment of Cancer CellsJournal of Materials Chemistry B2014, 2(36): 6064-71. DOI:  10.1039/C4TB01040J 

12 

 Xiaoxiao He, Yuhong Li, Dinggeng He, Kemin Wang*, Jingfang Shangguan and Hui Shi. Aptamer-Fluorescent Silica Nanoparticles Bioconjugates Based Dual-Color Flow Cytometry for Specific Detection of Staphylococcus AureusJournal of Biomedical Nanotechnology2014, 10(7): 1359-68. DOI: http://dx.doi.org/10.1166/jbn.2014.1828 

13 

 Xiaosheng Ye, Hui Shi, Xiaoxiao He, Kemin Wang*, Duo Li and Pengchao Qiu. Gold nanorod-seeded synthesis of Au@Ag/Au nanospheres with broad and intense near-infrared absorption for photothermal cancer therapyJournal of Materials Chemistry B2014, 2, 3667–3673. DOI:  10.1039/C4TB00202D 

14 

Qing Wang, Hui Wang, Xiaohai Yang, Kemin Wang*, Fang Liu, Qing Zhao, Pei Liu and Rongjuan Liu. Multiplex detection of nucleic acids using a low cost microfluidic chip and a personal glucose meter at the point-of-care. Chemical Communications2014, 50, 3824--3826. DOI:  10.1039/C4CC00133H 

15 

 Leiliang He, Xiaohai Yang, Kemin Wang*, Qing Wang, Fang Zhao, Jin Huang and Jianbo Liu. A self-assembled conformational switch: a host–guest stabilized triple stem molecular beacon via a photoactivated and thermal regeneration modeChemical Communications2014, 50, 7803--7805. DOI:  10.1039/C4CC01651C 

16 

 Dinggeng He, Xiaoxiao He, Kemin Wang*, Xue Yang, Xiaoxiao Yang, Xuecai Li and Zhen Zou. Nanometer-Sized Manganese Oxide-Quenched Fluorescent Oligonucleotides: An Effective Sensing Platform for Probing Biomolecular InteractionsChemical Communications2014, 50(75): 11049-52. DOI:  10.1039/C4CC04573D 

17 

 Zhihe Qing, Taiping Qing, Zhengui Mao, Xiaoxiao He, Kemin Wang*, Zhen Zou, Hui Shi and Dinggeng He. DsDNA-specific Fluorescent Copper Nanoparticles as a Green Nano-Dye for Polymerization-Mediated Biochemical AnalysisChemical Communications2014, 50(84): 12746-48. DOI:10.1039/C4CC05101G 

18 

 Jin Huang, Yong He, Xiaohai Yang, Kemin Wang*, Le Ying, Ke Quan, Yanjing Yang and Bincheng Yin. I-Motif-Based Nano-Flares for Sensing pH Changes in Live CellsChemical Communications2014, 50(99): 15768-71.DOI:  10.1039/C4CC08054H 

19 

Jianbo Liu, Pengfei Zhang, Xiaohai Yang, Kemin Wang, Qiuping Guo, Jin Huang, Wei Li. Aptamer-mediated indirect quantum dot labeling and fluorescent imaging of target proteins in living cells. Nanotechnology2014, 25, 50, 505502. DOI:10.1088/0957-4484/25/50/505502 

20 

Hui Shi, Xiaosheng Ye, Xiaoxiao He, Kemin Wang*, Wensi Cui, Dinggeng He, Duo Li and Xuekun Jia. Au@Ag/Au nanoparticles assembled with activatable aptamer probes as smart nano-doctors for image-guided cancer thermotherapyNanoscale2014, 6: 8754–8761.DOI:10.1039/C4NR01927J 

2013

1 

陈冕, 何晓晓, 石碧华, 王柯敏*,  陈素叶, 周冰不同尺寸二氧化硅纳米颗粒体内分布与代谢研究. 科学通报2013, 58(7): 568 -574.

2 

DingGeng He, Xiaoxiao He*, Kemin Wang*, YingXiang Zhao. A facile route for shape-selective synthesis of silica nanostructures using poly-L-lysine as templateChinese Chemical Letters2013, 24: 99-102. DOI: 10.1016/j.cclet.2013.01.038 

3 

Genping Yan, Yonghong Wang, Xiaoxiao He, Kemin Wang*, Jinquan Liu and Yudan Du. A highly sensitive label-free electrochemical aptasensor for interferon-gamma detection based on graphene controlled assembly and nuclease cleavage-assisted target recycling amplificationBiosensors and Bioelectronics2013, 44: 57-63. DOI: 10.1016/j.bios.2013.01.010 

4 

Jinjin Yin, Xiaoxiao He, Xuekun Jia, Kemin Wang* and Fengzhou Xu. Highly sensitive label-free fluorescent detection of Hg2+ ions by DNA molecular machine-based Ag nanoclustersAnalyst2013, 138: 2350-2356.  DOI: 10.1039/C3AN00029J 

   

5 

Kemin Wang*, Jin Huang, Xiaohai Yang, Xiaoxiao He and Jianbo Liu. Recent advances in fluorescent nucleic acid probes for living cell studiesAnalyst2013, 138: 62-71. DOI: 10.1039/C2AN35254K 

6 

 Dinggeng He, Xiaoxiao He, Kemin Wang*, Mian Chen, Yingxiang Zhao, Zhen Zou. Intracellular acid-triggered drug delivery system using mesoporous silica nanoparticles capped with T–Hg2+–T base pairs mediated duplex DNAJ. Mater. Chem. B2013,1 (11), 1552-1560. DOI: 10.1039/C3TB00473B 

7 

Jin Huang, Xiaohai Yang, Xiaoxiao He, Kemin Wang*, Yong He and Ke Quan. A new strategy for designing a graphene oxide-based DNA hairpin probe: fluorescence upon switching the orientation of the sticky endChemical Communications2013, 49: 9827-9829. DOI: 10.1039/C3CC45307C 

8 

 Xiaoxiao He, Chong Hu, Qian Guo, Kemin Wang*, Yuhong Li, Jingfang Shangguan. Rapid and ultrasensitive Salmonella Typhimurium quantification using positive dielectrophoresis driven on-line enrichment and fluorescent nanoparticles labelBiosensors and Bioelectronics2013, 42: 460-466. DOI: 10.1016/j.bios.2012.11.020 

9 

 Yonghong Wang, Xiaoxiao He, Kemin Wang*, Jing Su, Zhifeng Chen, Genping Yan, Yudan Du. A label-free electrochemical assay for methyltransferase activity detection based on the controllable assembly of single wall carbon nanotubesBiosensors and Bioelectronics, 2013, 41: 238-243. DOI: 10.1016/j.bios.2012.08.034 

10 

Zhifeng Chen, Xiaoxiao He, Yonghong Wang, Kemin Wang*, Yudan Du and Genping Yan. Ru(II) encapsulated phosphorylate-terminated silica nanoparticles-based electrochemiluminescent strategy for label-free assay of protein kinase activity and inhibitionBiosensors and Bioelectronics2013, 41: 519-525. DOI: 10.1016/j.bios.2012.09.018 

11 

         Kemin Wang*, Xiaoxiao He, Xiaohai Yang and Hui Shi. Functionalized Silica Nanoparticles: A Platform for Fluorescence Imaging at the Cell and Small Animal LevelsAccounts of Chemical Research2013, 46(7):1367-1376. DOI: 10.1021/ar3001525 

2012

1 

 Jianbo Liu, Xiaohai Yang, Kemin Wang*, Yan He, Pengfei Zhang, Haining Ji, Lixin Jian, Wei Liu. Single nanoparticle imaging and characterization of different phospholipid-encapsulated quantum dot micelles. Langmuir2012, 28 (28): 10602-10609. DOI: 10.1021/la301873m 

2 

 Dinggeng He, Xiaoxiao He*, Kemin Wang*, Jie Cao, Yingxiang Zhao. A light-responsive reversible molecule-gated system using thymine-modified mesoporous silica nanoparticles. Langmuir2012, 28 (8): 4003-4008.

3 

Fang Ren, Xiaoxiao He*, Kemin Wang*, Jinjin Yin. Biosynthesis of gold nanoparticles using catclaw buttercup (Radix Ranunculi Ternati) and colloid stabilityJournal of Biomedical Nanotechnology2012, 8(4): 586-593. DOI: http://dx.doi.org/10.1166/jbn.2012.1417 

4 

 Fengzhou Xu, Hui Shi, Xiaoxiao He, Kemin Wang*, Xiaosheng Ye, Lv’an Yan, Shuyong Wei. A facile graphene oxide-based DNA polymerase assayAnalyst, 2012,137 (17):3989-3994. DOI: 10.1039/C2AN35585J 

5 

 Jinjin Yin, Xiaoxiao He, Kemin Wang*, Zhihe Qing, Xu Wu, Hui Shi, Xiaohai Yang. One-step engineering of silver nanoclusters-aptamer assemblies as luminescent labels to target tumor cells.  Nanoscale2012, 4 (1): 110-112. DOI: 10.1039/C1NR11265A 

6 

 Dinggeng Xiaoxiao He He, Kemin Wang*, Mian Chen, Jie Cao, Yingxiang Zhao. Reversible stimuli-responsive controlled release using mesoporous silica nanoparticles functionalized with a smart DNA molecule-gated switchJournal of Materials Chemistry2012, 22 (29): 14715-14721. DOI: 10.1039/C2JM32185H 

7 

 Jianbo Liu, Xiaohai Yang, Kemin Wang*, Qing Wang, Haining Ji, Chunlei Wu, Jing Li, Xiaoxiao He, Jinlu Tang, Jin Huang. Combining physical embedding and covalent bonding for stable encapsulation of quantum dots into agarose hydrogelsJournal of Materials Chemistry2012, 22 (2):495-501.  DOI: 10.1039/C1JM13090K 

8 

 Jing Su, Xiaoxiao He, Yonghong Wang, Kemin Wang*, Zhifeng Chen, Genping Yan. A sensitive signal-on assay for MTase activity based on methylation-responsive hairpin-capture DNA probe. Biosensors and Bioelectronics2012, 36(1): 123-128. DOI: 10.1016/j.bios.2012.04.012 

9 

 Xiaoxiao He, Zhifeng Chen, Yonghong Wang, Kemin Wang*, Jing Su, Genping Yan. TiO2/MWNTs nanocomposites-based electrochemical strategy for label-free assay of casein kinase II activity and inhibitionBiosensors and Bioelectronics2012, 35(1): 134-139. DOI: 10.1016/j.bios.2012.02.032 

10 

 Yonghong Wang, Xiaoxiao He*, Kemin Wang*, Xiaoqi Ni, Jing Su, Zhifeng Chen. Ferrocene-functionalized SWCNT for electrochemical detection of T4 polynucleotide kinase activityBiosensors and Bioelectronics, 2012, 32 (1): 213-218. DOI: 10.1016/j.bios.2011.12.012 

11 

 Xiaoxiao He, Yushuang Wang, Kemin Wang*, Mian Chen, Suye Chen. Fluorescence resonance energy transfer mediated large stokes shifting near-infrared fluorescent silica nanoparticles for in vivo small-animal imagingAnalytical Chemistry2012, 84 (21): 9056-9064. DOI: 10.1021/ac301461s 

12 

Qing Wang, Lijuan Yang, Xiaohai Yang, Kemin Wang*, Leiliang He, Jinqing Zhu, Tianyuan Su. An electrochemical DNA biosensor based on the ‘‘Y’’ junction structure and restriction endonuclease-aided target recycling strategyChemical Communications, 2012, (48): 2982-2984. DOI: 10.1039/C2CC17679C 

13 

 Dinggeng He, Xiaoxiao He, Kemin Wang*, Jie Cao, Yingxiang Zhao. A photon-fueled gate-like delivery system using i-motif DNA functionalized mesoporous silica nanoparticles. Advanced Functional Materials, 2012, 22 (22): 4704-4710. DOI: 10.1002/adfm.201201343 

14 

 Jianbo Liu, Xiaohai Yang, Kemin Wang*, Xiaoxiao He, Qing Wang, Jin Huang, Yan Liu. Aggregation control of quantum dots through ion-mediated hydrogen bonding shieldingACS Nano2012, 6 (6): 4973-4983. DOI: 10.1021/nn300517k 

2011

1 

Xiaorong Zhang, Xiaoxiao He, Kemin Wang*, Fang Ren, Zhihe Qin. pH induced protein-scaffold biosynthesis of tunable shape gold nanoparticlesNanotechnology2011, 22 (35): 355603. doi: 10.1088/0957-4484/22/35/355603 

2 

 Qing Wang, Lijuan Yang, Xiaohai Yang, Kemin Wang*, Leiliang He, Jinqing Zhu. Electrochemical biosensors for detection of point mutation based on surface ligation reaction and oligonucleotides modified gold nanoparticles. Analytica Chimica Acta2011, 688 (2) :163-167. doi:10.1016/j.aca.2011.01.004 

3 

Xiaorong Zhang, Xiaoxiao He, Kemin Wang*, Xiaohai Yang. Different active biomolecules involved in biosynthesis of gold nanoparticles by three fungus species. Journal of biomedical nanotechnology, 2011, 7 (2): 245-254. DOI: ttp://dx.doi.org/10.1166/jbn.2011.1285 

4 

 Xiaoxiao He, Lixia Zhou, Dinggeng He, Kemin Wang*, Jie Cao. Rapid and ultrasensitive E. coli O157:H7 quantitation by combination of ligandmagnetic nanoparticles enrichment with fluorescent nanoparticles based two-color flow cytometryAnalyst2011, 136 (20): 4183-4191. DOI: 10.1039/C1AN15413C 

5 

Xiaoxiao He, Luo Hai, Jing Su, Kemin Wang*, Xu Wu. One-pot synthesis of sustained-released doxorubicin silica nanoparticles for aptamer targeted delivery to tumor cells. Nanoscale, 2011, 3 (7) : 2936-2942. DOI: 10.1039/C0NR00913J 

6 

 Jin Huang, Yan Chen, Liu Yang, Zhi Zhu, Guizhi Zhu, Xiaohai Yang, Kemin Wang*, Weihong Tan*. Amplified detection of cocaine based on strand-displacement polymerization and fluorescence resonance energy transfer.  Biosensors and Bioelectronic2011, 28 (1): 450-453. DOI: 10.1016/j.bios.2011.05.038 

7 

 Xiaoxiao He, Jing Su, Yonghong Wang, Kemin Wang*, Xiaoqi Ni, Zhifeng Chen. A sensitive signal-on electrochemical assay for Mtase activity using AuNPs amplificationBiosensors and Bioelectronics2011, 28 (1): 298-303. DOI:10.1016/j.bios.2011.07.035 

8 

Yonghong Wang, Xiaoxiao He*, Kemin Wang*, Xiaoqi Ni, Jing Su, Zhifeng Chen. Electrochemical detection of thrombin based on aptamer and ferrocenylhexanethiol loaded silica nanocapsulesBiosensors and Bioelectronics2011, 26 (8): 3536-3541. doi:10.1016/j.bios.2011.01.041 

9 

Jing Zheng, Jishan Li, Ying Jiang, Jianyu Jin, Kemin Wang, Ronghua Yang*, Weihong Tan. Design aptamer-based sensing platform using triple-helix molecular switchAnalytical Chemistry2011, 83(17): 6586-6592. DOI: 10.1021/ac201314y 

10 

 Zhiwen Tang, Pei Liu, Changbei Ma, Xiaohai Yang, Kemin Wang*, Weihong Tan, Xiaoyuan Lv. Molecular beacon based bioassay for highly sensitive and selective detection of nicotinamide adenine dinucleotide and the activity of alanine aminotransferaseAnalytical Chemistry2011, 83(7): 2505-2510. DOI: 10.1021/ac102742k 

11 

 Jianbo Liu, Xiaohai Yang, Kemin Wang*, Ronghua Yang, Haining Ji, Liyan Yang, Chunlei Wu. A switchable fluorescent quantum dot probe based on aggregation/disaggregation mechanismChemical Communications, 2011, 47(3): 935-937. DOI: 10.1039/C0CC03993D 

12 

Liu Yang, Xiaobing Zhang, Mao Ye, Jianhui Jiang, Ronghua Yang, Ting Fu, Yan Chen, Kemin Wang, Chen Wei Liuhong Tan*. Aptamer-conjugated nanomaterials and their applicationsAdvanced drug delivery reviews2011, 63(14–15): 1361–1370. doi:10.1016/j.addr.2011.10.002 

13 

Jin Huang, Yanrong Wu, Yan Chen, Zhi Zhu, Xiaohai Yang, Chaoyong James Yang*, Kemin Wang*, Weihong Tan*. Pyrene-excimer probes based on the hybridization chain reaction for the detection of nucleic acids in complex biological fluids. Angewandte Chemie International Edition2011,50 (2): 401-404.DOI: 10.1002/anie.201005375 

14 

 Hui Shi, Xiaoxiao He, Kemin Wang*, Xu Wu, Xiaosheng Ye, Qiuping Guo, Weihong Tan, Zhihe Qing, Xiaohai Yang, Bing Zhou. Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alterationProceedings of the National Academy of Sciences2011, 108 (10): 3900-3905. DOI: 10.1073/pnas.1016197108 

2010

1 

Xiaohai Yang, Wenjuan Yang, Qing Wang, Huimin Li, Kemin Wang*, Liu Yang, Wei Liu. Atomic force microscopy investigation of the characteristic effects of silver ions on Escherichia coli and Staphylococcus epidermidisTalanta2010, 81 (4-5) : 1508-1512. doi:10.1016/j.talanta.2010.02.061 

2 

Xiangxian Meng, Xiaohai Yang, Kemin Wang*, Qiuping Guo, Yongjun Tan, Qiuhua Mo, Xiangmin Xu. Direct fluorescence detection of point mutations in human genomic DNA using microbead-based ligase chain reactionTalanta2010, 80(5): 1725-1729. DOI: 10.1016/j.talanta.2009.10.013 

3 

 Xiaoxiao He, Feng Xuan, Kemin Wang*, Yongjin Yuan, Xin Cheng. Chemical-modification-enhanced dielectrophoretic assembly of controllable and reversible silica submicrowires from nanoparticlesLangmuir2010, 26 (19): 15155-15160. DOI: 10.1021/la1019636 

4 

Chunyan Tan, Yonghua Xie, Xiaoxiao He, Kemin Wang*, Yuyang Jiang*. Hyper-efficient quenching of a conjugated polyelectrolyte by dye-doped silica nanoparticles: Better quenching in the nonaggregated stateLangmuir2010, 26 (3): 1528-1532. DOI: 10.1021/la903970t 

5 

Hui Shi, Zhiwen Tang, Youngmi Kim, Hailong Nie, Yu Fen Huang, Xiaoxiao He, Ke Deng, Kemin Wang*, Weihong Tan*. In vivo fluorescence imaging of tumors using molecular aptamers generated by cell-SELEXChemistry – An Asian Journal, 2010, 5 (10): 2209-2213. DOI: 10.1002/asia.201000242 

6 

Dan Liu, Xiaoxiao He*, Kemin Wang*, Chunmei He, Hui Shi, Lixin Jian. Biocompatible silica nanoparticles−insulin conjugates for mesenchymal stem cell adipogenic differentiationBioconjugate chemistry2010, 21 (9): 1673-1684. DOI: 10.1021/bc100177v 

7 

 Xu Wu, Xiaoxiao He*, Kemin Wang*, Can Xie, Bing Zhou, Zhihe Qing. Ultrasmall near-infrared gold nanoclusters for tumor fluorescence imaging in vivo. Nanoscale2010, 2 (10): 2244-2249. DOI: 10.1039/C0NR00359J 

8 

Yonghong Wang, Xiaoxiao He, Kemin Wang*, Xiaoqi Ni. A sensitive ligase-based ATP electrochemical assay using molecular beacon-like DNABiosensors and Bioelectronics2010, 25 (9):2101-2106. DOI:10.1016/j.bios.2010.02.007 

9 

Jin Huang, Zhi Zhu, Suwussa Bamrungsap, Guizhi Zhu, Mingxu You, Xiaoxiao He, Kemin Wang*, Weihong Tan*. Competition-mediated pyrene-switching aptasensor: Probing lysozyme in human serum with a monomer-excimer fluorescence switchAnalytical Chemistry2010, 82 (24):10158-10163. DOI: 10.1021/ac102277p 

10 

Hao Wang, Jishan Li, Yongxiang Wang, Jiangyu Jin, Ronghua Yang*, Kemin Wang*, Weihong Tan. Combination of DNA ligase reaction and gold nanoparticle-quenched fluorescent oligonucleotides: A simple and efficient approach for fluorescent assaying of single-nucleotide polymorphismsAnalytical Chemistry2010, 82 (18): 7684-7690. DOI: 10.1021/ac101503t 

11 

 Yongxiang Wang, Jishan Li, Hao Wang, Jianyu Jin, Jinhua Liu, Kemin Wang, Weihong Tan, Ronghua Yang*. Silver ions-mediated conformational switch: Facile design of structure-controllable nucleic acid probesAnalytical Chemistry2010, 82 (15): 6607-6612. DOI: 10.1021/ac101114w 

12 

Jing Zheng, Jishan Li, Xiaoxia Gao, Jianyu Jin, Kemin Wang, Weihong Tan, Ronghua Yang*. Modulating molecular level space proximity: A simple and efficient strategy to design structured DNA probesAnalytical Chemistry2010, 82 (9): 3914-3921.DOI: 10.1021/ac1004713 

13 

Hui Shi, Xiaoxiao He, Yuan Yuan, Kemin Wang*, Dan Liu. Nanoparticle-based biocompatible and long-life marker for lysosome labeling and tracking. Analytical Chemistry2010, 82 (6): 2213-2220. DOI: 10.1021/ac902417s 

14 

 Xiaoxiao He, Kemin Wang*, Zhen Cheng. In Vivo near-infrared fluorescence imaging of cancer with nanoparticle-based probesWiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2010, 2(4): 349-366. DOI: 10.1002/wnan.85 

2009

1 

 羊小海, 王胜锋, 王柯敏*, 罗晓明, 谭蔚泓, 崔亮基于阳离子荧光共轭聚合物和核酸适体探针的蛋白质检测新方法高等学校化学学报2009,30 (5): 899-902.

2 

 何晓晓, 海罗, 王柯敏*, 伍旭, 谭蔚泓基于磷酸化修饰的核/壳硅纳米颗粒药物缓释体研究. 高等学校化学学报2009,30 (2): 283-288.

3 

 Xiangxian Meng, Xiaohai Yang, Kemin Wang*, Weihong Tan, Qiuping Guo. Real-time monitoring of DNAzyme cleavage process using fluorescent assay. Chinese Chemical Letters2009, 20 (8): 990-994. doi:10.1016/j.cclet.2009.03.028 

4 

 Xiaorong Zhang, Xiaoxiao He, Kemin Wang*, Yonghong Wang, Huimin Li, Weihong Tan. Biosynthesis of size-controlled gold nanoparticles using fungus, Penicillium sp. Journal of Nanoscience and Nanotechnology2009, 9 (10): 5738-5744. DOI: http://dx.doi.org/10.1166/jnn.2009.1287 

5 

 Huimin Li, Meijun Diao, Shouchun Zhang, Kemin Wang*, Caoye Xue. Novel polymeric micelles of AB(2) type alpha-methoxy-poly(ethylene glycol)-b-poly(gamma-benzyl-L-glutamate)(2) copolymers as tamoxifen carriers. Journal of Nanoscience and Nanotechnology2009, 9 (8): 4805-4811. DOI: http://dx.doi.org/10.1166/jnn.2009.1098 

6 

 Xiaohai Yang, Xiang Zhao, Xinbing Zuo, Kemin Wang*, Jianhui Wen, He Zhang. Nucleic acids detection using cationic fluorescent polymer based on one-dimensional microfluidic beads array. Talanta2009, 77 (3): 1027-1031. doi:10.1016/j.talanta.2008.08.001 

7 

 Yonghong Wang, Xiaoxiao He*, Kemin Wang*, Xiaorong Zhang, Weihong Tan. Barbated Skullcup herb extract-mediated biosynthesis of gold nanoparticles and its primary application in electrochemistry. Colloids and Surfaces B: Biointerfaces2009, 73 (1): 75-79. doi:10.1016/j.colsurfb.2009.04.027 

8 

 Parviz Ashtari*, Kemin Wang, Xiaohai Yang, Seyed Javad Ahmadi. Preconcentration and separation of ultra-trace beryllium using quinalizarine-modified magnetic microparticles. Analytica Chimica Acta2009, 646 (1-2): 123-127. doi:10.1016/j.aca.2009.05.004 

9 

 Ping Wu, Xiaoxiao He, Kemin Wang*, Weihong Tan, Chunmei He, Mingbin Zheng. A novel methotrexate delivery system based on chitosan-methotrexate covalently conjugated nanoparticles. Journal of Biomedical Nanotechnology2009, 5 (5): 557-564. DOI: http://dx.doi.org/10.1166/jbn.2009.1073 

10 

 Xiaoxiao He, Xu Wu, Kemin Wang*, Bihua Shi, Luo Hai. Methylene blue-encapsulated phosphonate-terminated silica nanoparticles for simultaneous in vivo imaging and photodynamic therapy. Biomaterials2009, 30 (29): 5601-5609. doi:10.1016/j.biomaterials.2009.06.030 

11 

 Yongxiang Wang, Jishan Li, Jianyu Jin, Hao Wang, Hongxing Tang, Ronghua Yang*, Kemin Wang*. Strategy for molecular beacon binding readout: Separating molecular recognition element and signal reporter. Analytical Chemistry2009, 81 (23) ): 9703-9709. DOI: 10.1021/ac901906w 

12 

 Jianbo Liu, Xiaohai Yang, Kemin Wang*, Dong Wang, Pengfei Zhang. Chemical etching with tetrafluoroborate: a facile method for resizing of CdTe nanocrystals under mild conditions. Chemical Communications2009, (40): 6080-6082.DOI: 10.1039/B910752E 

13 

 Qiuping Guo, Xiaohai Yang, Kemin Wang*, Weihong Tan, Wei Li, Hongxing Tang, Huimin Li. Sensitive fluorescence detection of nucleic acids based on isothermal circular strand-displacement polymerization reactionNucleic Acids Research2009, 37 (3): e20. doi: 10.1093/nar/gkn1024 

14 

Kemin Wang*, Zhiwen Tang, Chaoyong James Yang, Youngmi Kim, Xiaohong Fang, Wei Li, Yanrong Wu, Colin D. Medley, Zehui Cao, Jun Li, Patrick Colon, Hui Lin, Weihong Tan*. Molecular engineering of DNA: molecular beaconsAngewandte Chemie International Edition2009, 48 (5): 856-870. DOI: 10.1002/anie.200800370 

All

Full Publications List (1986 — 2016)