Jianbo Liu (刘剑波)
Ph D, Professor,
College of Chemistry and Chemical Engineering,
State Key Laboratory of Chemo/Biosensing and Chemometrics,
Hunan University
Addree: A101, Nanomedicine Building, Hunan University (410082)
Email: liujianbo@hnu.edu.cn
Lab Website: http://grjl.hnu.edu.cn/JianboLiu
Brief Introduction
Dr. Jianbo Liu is a professor at the College of Chemistry and Chemical Engineering at Hunan University, where he serves as the Chair of the Department of Chemical Biology and Molecular Medicine. He is a core member of the State Key Laboratory of Chemo/Biosensing. He received his Bachelor's and Doctorate degrees from Hunan University in 2004 and 2011 (Supervisor: Prof. Kemin Wang), respectively, and has been on the faculty since graduation. From 2017 to 2019, he conducted postdoctoral research at the University of Bristol, UK (Supervisor: Stephen Mann FRS).
Dr. Liu's research focuses on chemical biology and analytical chemistry, involving the design of synthetic protocell/artificial cell and prototissue for drug delivery, and disease diagnosis.. Dr. Liu has published more than 60 as the corresponding author in prestigious journals such as Nat. Chem, PNAS, Nat. Commun., JACS, and Angew. Chem.
Dr. Liu has been recognized with numerous awards, including the Ministry of Education Young Changjiang Scholar (2022), China's Top Ten Emerging Scientists (2021), Hunan Province Science and Technology Innovation Leading Talent (2022), and Hunan Province Outstanding Youth Fund (2021).
Research Areas
Chemical Biology: Chemical construction of synthetic cells for therapeutic applications. We focus on the chemical construction of artificial cells, aiming to develop modules for compartmentalization, signal transduction, and metabolic regulation. These artificial cells are designed to replace dysfunctional cells, restore metabolic balance, and offer innovative tools for disease treatment.
Analytical Chemistry: Design of nanoprobe for optical imaging and biosensing. Our research develops novel nano-probes and techniques for optical imaging and chemo-biological analysis. We emphasize in situ, real-time studies, advancing highly sensitive fluorescence analysis and whole-cell sensing technologies for dynamic and efficient environmental monitoring.
Recruitment
The research group is actively recruiting for positions including Associate Professor, Lecturer, Postdoctoral Fellow, and Research Assistant (ongoing). Each year, we accept 2-3 doctoral and master's students. Undergraduate students and joint training students are welcome. Candidates with backgrounds in chemistry, biology, or materials science are especially encouraged to apply.
Group photo
Cover illustrations
A video for the illustration of Nat. Chem. (2020)
Cover publications
Selected publication
More than 100 academic paper，with 60 papers as first authors and corresponding authors.
URL: http://www.researcherid.com/rid/K-1959-2016
ORCID:https://orcid.org/0000-0001-8282-4078
2024
[58] Xiaohong Wen, Zhixiang Huang, Xiaohai Yang, Xiaoxiao He, Lie Li, Haiyan Chen, Kemin Wang,* Qiuping Guo,* Jianbo Liu* Development of an Aptamer Capable of Multidrug Resistance Reversal for Tumor Combination Chemotherapy. Proceedings of the National Academy of Sciences of the United States of America 2024, 121, e2321116121. https://doi.org/10.1073/pnas.2321116121
[57] Ya Wang, Yamin Xiong, Kangqi Shi, Clement Yaw Effah, Lulu Song, Leiliang He,* Jianbo Liu* DNA nanostructures for exploring cell–cell communication. Chemical Society Reviews 2024, Advance Article. https://doi.org/10.1039/D3CS00944K
[56] Kleins Ngocho, Xilei Yang, Zefeng Wang, Cunjie Hu, Xiaohai Yang, Hui Shi,* Kemin Wang, Jianbo Liu* Synthetic cells from droplet-based microfluidics for biosensing and biomedical applications. Small, 2024, Dol:10.1002/sml.202400086
2023
[55] Hui Chen, Wanyu Xu, Hui Shi, Yan Qiao, Xiaoxiao He, Jing Zheng, Shaohong Zhou, Xiaohai Yang, Kemin Wang, Jianbo Liu*. DNA-based artificial receptors as transmembrane signal transduction systems for protocellular communication. Angewandte Chemie International Edition, 2023, 62, e202301559.
[54] Yanwen Zhang#, Zefeng Wang#, Mei Li, Can Xu, Ning Gao, Zhuping Yin, Kemin Wang, Stephen Mann,* Jianbo Liu.* Osmotic-induced reconfiguration and activation in membranized coacervate-based protocells. Journal of the American Chemical Society. Accepted, DOI: 10.1021/jacs.3c02540, ASAP.
[53] Zefeng Wang, Min Zhang, Yan Zhou, Yanwen Zhang, Kemin Wang, Jianbo Liu*. Coacervate microdroplets as synthetic protocells for cell mimicking and signaling communications. Small Methods, 2023, 7, 2300042.
[52] Yanwen Zhang, Shixin Wang, Yuling Yan, Xiaoxiao He, Zefeng Wang, Shaohong Zhou, Xiaohai Yang, Kemin Wang, Jianbo Liu*. Phase-separated bienzyme compartmentalization as artificial intracellular membraneless organelles for cell repair. Science China Chemistry, 2023, 66, 845-852. https://doi.org/10.1007/s11426-022-1491-0
[51] Yang Li, Songyang Liu, Wanyu Xu, Kemin Wang, Fengjiao He,* Jianbo Liu.* Formation of giant plasma membrane vesicles for biological and medical applications: a review. Sensors & Diagnostics, 2023, Accepted Manuscript. DOI: 10.1039/D3SD00060E.
[50] Wanyu Xu, Hui Chen, Yang Li, Shuangna Liu, Kemin Wang,* Jianbo Liu* Design of DNA-based artificial transmembrane channels for biosensing and biomedical applications. Chemosensors 2023, 11, 508; https://doi.org/10.3390/chemosensors11090508
2022
[49] Songyang Liu, Yanwen Zhang, Xiaoxiao He, Mei Li, Jin Huang, Xiaohai Yang, Kemin Wang, Stephen Mann*, Jianbo Liu* Signal processing and generation of bioactive nitric oxide in a model prototissue. Nature Communications, 2022, 13, 5254. https://www.nature.com/articles/s41467-022-32941-6
[48] Yufeng Chen, Min Yuan, Yanwen Zhang, Shaohong Zhou, Kemin Wang, Zhenjun Wu*, Jianbo Liu.* Enzyme-active liquid coacervate microdroplets as artificial membraneless organelles for intracellular ROS scavenging. Biomaterial Science 2022,10, 4588-4595.
[47] Shaohong Zhou, Xueer Cai, Yanwen Zhang, Qiaoshu Chen, Xiaohai Yang, Kemin Wang, Lixin Jian,* Jianbo Liu* DNA nanotubes in coacervate microdroplets as biomimetic cytoskeletons modulate the liquid fluidic properties of protocells. Journal of Materials Chemistry B, 2022, 10, 8322-8329.
[46] Xue'er Cai, Meiling Jian, Shaohong Zhou, Zefeng Wang, Kemin Wang, Jianbo Liu.* Chemical construction of artificial cells and their biomedical applications. Progress in Chemistry, 2022, 34, 2462-2475. DOI: 10.7536/PC220308.
2021
[45] Hui Chen, Li Zhou (co-author), Chunying Li, Xiaoxiao He, Jin Huang, Xiaohai Yang, Hui Shi,* Kemin Wang, Jianbo Liu.* Controlled dimerization of artificial membrane receptors for transmembrane signal transduction. Chemical Science, 2021, 12, 8224-8230. https://doi.org/10.1039/D1SC00718A
[44] Yanwen Zhang, Yufeng Chen, Xiaohai Yang, Xiaoxiao He, Mei Li, Songyang Liu, Kemin Wang, Jianbo Liu*, Stephen Mann.* Giant coacervate vesicles as an integrated approach to cytomimetic modeling. Journal of the American Chemical Society, 2021, 143, 2866−2874. https://doi.org/10.1021/jacs.0c12494
[43] Yanwen Zhang, Yu Yao, Songyang Liu, Yufeng Chen, Shaohong Zhou, Kemin Wang, Xiaohai Yang,* Jianbo Liu.* Coacervate microdroplet protocells-mediated gene transfection for nitric oxide production and induction of cell apoptosis. Journal of Materials Chemistry B, 2021, 9, 9784-9793. https://pubs.rsc.org/en/content/articlehtml/2021/tb/d1tb01930a
[42] Qiaoshu Chen, Meiling Jian, Hui Chen, Bing Zhou, Hui Shi, Xiaohai Yang, Kemin Wang, Jianbo Liu.* Design of lipophilic split aptamers as artificial carriers for transmembrane transport of adenosine triphosphate. CCS Chemistry, 2021, 3, 144-153. https://doi.org/10.31635/ccschem.020.202000591
[41] Qiaoshu Chen, Yanwen Zhang, Hui Chen, Jianbo Liu,* Juewen Liu.* Enhancing the sensitivity of DNA and aptamer probes in the Dextran/PEG aqueous two-phase system. Analytical Chemistry, 2021, 93, 8577–8584. https://doi.org/10.1021/acs.analchem.1c01419
[40] Yu Yao#, Yanwen Zhang (co-author)#, Li Li, Yan Huang, Xiaohai Yang, Zhihong Peng,* Kemin Wang, Jianbo Liu.* Photothermally activated coacervate model protocells as signal transducers endow mammalian cells with light sensitivity. Advanced Biology, 2021, 5, 2100695. https://doi.org/10.1002/adbi.202100695.
[39] Chunying Li, Hui Chen, Xiaohai Yang,* Kemin Wang, Jianbo Liu.* An ion transport switch based on light-responsive conformation-dependent G-quadruplex transmembrane channels. Chemical Communications, 2021, 57, 8214-8217. https://doi.org/10.1039/D1CC03273A
[38] Yufeng Chen, Yanwen Zhang, Mei Li, Songyang Liu, Xiaohai Yang, Kemin Wang, Stephen Mann,* Jianbo Liu.* Self-immobilization of coacervate droplets by enzyme-mediated hydrogelation. Chemical Communications, 2021,57, 5438-5441. https://doi.org/10.1039/D1CC01483H
2020
[37] Songyang Liu, Yanwen Zhang, Mei Li, Li Xiong, Zijian Zhang, Xiaohai Yang, Xiaoxiao He, Kemin Wang, Jianbo Liu,* Stephen Mann.* Enzyme-mediated nitric oxide production in vasoactive erythrocyte membrane-enclosed coacervate protocells. Nature Chemistry, 2020, 12, 1165-1173. https://www.nature.com/articles/s41557-020-00585-y
[36] Jianbo Liu,* Liangfei Tian, Yan Qiao, Shaohong Zhou, Avinash J. Patil, Kemin Wang, Mei Li,* Stephen Mann.* Hydrogel-immobilized coacervate droplets as modular microreactor assemblies. Angewandte Chemie International Edition, 2020, 59, 6853 – 6859. (Hot paper, Cover Article)
[35] Yanwen Zhang, Songyang Liu, Yu Yao, Yufeng Chen, Shaohong Zhou, Xiaohai Yang, Kemin Wang,* Jianbo Liu.* Invasion and defense interactions between enzyme-active liquid coacervate protocells and living cells. Small, 2020, 16, 20020733 (Cover Article).
[34] Yufeng Chen, Min Yuan, Yanwen Zhang, Songyang Liu, Xiaohai Yang, Kemin Wang,* Jianbo Liu.* Construction of coacervate-in-coacervate multicompartment protocells for spatial organization of enzymatic reactions. Chemical Science, 2020, 11, 8617–8625.
[33] Chunying Li, Hui Chen, Qiaoshu Chen, Hui Shi,* Xiaohai Yang, Kemin Wang, Jianbo Liu.* Lipophilic G-quadruplex isomers as biomimetic ion channels for conformation- dependent selective transmembrane transport. Analytical Chemistry, 2020, 92, 10169–10176.
[32] Qiaoshu Chen, Yibo Liu, Jianbo Liu,* Juewen Liu.* Liposome boosted peroxidase mimicking nanozymes breaking the pH limit. Chemistry - A European Journal, 2020, 26, 16659-16665 (Hot paper).
[31] Yingben Wu,* Yan Liu (co-author), Huizhi Liu, Biao Liu, Wei Chen, Lijuan Xu, Jianbo Liu.* Ion-mediated self-assembly of Cys-capped quantum dots for fluorescence detection of As(III) in water. Analytical Methods, 2020, 12, 4229–4234.
[30] Yan Huang, Haifeng Li, Xiaoxiao He, Xiaohai Yang, Li Li, Songyang Liu, Zhen Zou, Kemin Wang,* Jianbo Liu.* Near-infrared photothermal release of hydrogen sulfide from nanocomposite hydrogels for anti-inflammation applications. Chinese Chemical Letters, 2020, 31, 787-791.
2019
[29] Miaomiao Zhuang, Yanwen Zhang, Shaohong Zhou, Yun Zhang, Kemin Wang, Jinfang Nie,* Jianbo Liu.* Uricase-containing coacervate microdroplets as enzyme active membrane-free protocells for detoxification of uric acid in serum. Chemical Communications, 2019, 55, 13880-13883.
[28] Chunying Li, Hui Chen, Li Zhou, Hui Shi, Xiaoxiao He, Xiaohai Yang,* Kemin Wang, Jianbo Liu.* Single-stranded DNA designed lipophilic G-quadruplexes as transmembrane channels for switchable potassium transport. Chemical Communications, 2019, 55, 12004-12007. (Cover Page)
[27] Haifeng Li, Yu Yao, Hui Shi, Yanli Lei, Yan Huang, Kemin Wang, Xiaoxiao He,* Jianbo Liu.* Near-infrared light-responsive nanocomposite for photothermal release of H2S and suppression of cell viability. Journal of Materials Chemistry B, 2019, 7, 5992-5997.
[26] Qiaoshu Chen, Shaohong Zhou, Chunying Li, Qiuping Guo, Xiaohai Yang, Jin Huang, Jianbo Liu,* Kemin Wang.* DNA supersandwich assemblies as artificial receptors to mediate intracellular delivery of catalase for efficient ROS scavenging. Chemical Communications, 2019, 55, 4242-4245.
2018 and before
[25] Li Li, Gui Li, Xiaoxiao He, Xiaohai Yang, Songyang Liu, Jinlu Tang, Qiaoshu Chen, Jianbo Liu,* Kemin Wang.* Protein- driven disassembly of surfactant- polyelectrolyte nanomicelles: Modulation of quantum dot/fluorochrome FRET for pattern sensing. Sensors and Actuators B: Chemical, 2018, 272, 393-399.
[24] Li Zhou, Yu Liu, Hui Shi, Xiaohai Yang, Jin Huang, Songyang Liu, Qiaoshu Chen, Jianbo Liu,* Kemin Wang.* Flexible assembly of an enzyme cascade on a DNA triangle prism nanostructure for the controlled biomimetic generation of nitric oxide. ChemBioChem. 2018, 19, 2099-2106.
[23] Wei Liu, Jue Zhang, Zhihong Peng, Xiaohai Yang, Li Li, Qiaoshu Chen, Jianbo Liu,* Kemin Wang.* Controlled formation of Ag2S/Ag Janus nanoparticles using alkylamine as reductant surfactants. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2018, 544, 111-117.
[22] Qiaoshu Chen, Chunying Li, Xiaohai Yang, Jin Huang, Songyang Liu, Wei Liu, Jianbo Liu,* Kemin Wang*. Self-assembled DNA nanowires as quantitative dual-drug nanocarriers for antitumor chemophotodynamic combination therapy. Journal of Materials Chemistry B, 2017, 5, 7529-7537.
[21] Yu Liu，Qiaoshu Chen，Xiaohai Yang，Qiuping Guo，Li Li, Jianbo Liu,* Kemin Wang*. Design of modular DNA triangular-prism sensor enabling ratiometric and multiplexed biomolecule detection on single microbead. Analytical Chemistry，2017, 89, 3590−3596.
[20] Xi Guo, Yanwen Zhang, Jianbo Liu,*Xiaohai Yang, Jin Huang, Li Li, Lan Wan, Kemin Wang.* Red blood cell membrane-mediated fusion of hydrophobic quantum dots with living cell membranes for cell imaging. Journal of Materials Chemistry B, 2016, 4, 4191-4197.
[19] Lan Wan, Qiaoshu Chen, Jianbo Liu,* Xiaohai Yang, Jin Huang, Li Li, Xi Guo, Jue Zhang, Kemin Wang* Programmable self-assembly of DNA-protein hybrid hydrogel for enzyme encapsulation with enhanced biological stability. Biomacromolecules, 2016, 17, 1543–1550.
[18] Li Li, Jianbo Liu*, Xiaohai Yang, Jin Huang, Dinggeng He, Xi Guo, Lan Wan, Xiaoxiao He,* Kemin Wang* Biomimetic synthesis of highly biocompatible gold nanoparticles with amino acid-dithiocarbamate as a precursor for SERS imaging. Nanotechnology, 2016, 27, 105603.
[17] Xing Shi, Jue Zhang, Xiaohai Yang, Wei Liu, Li Li, Gui Li, Jianbo Liu,* Kemin Wang* Metallurgical leaching of metal powder for facile and generalized synthesis of metal sulfide nanocrystals. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2016, 497, 344–351
[16] Wei Liu, Xiaohai Yang, Dinggeng He, Leiliang He, Li Li, Yu Liu, Jianbo Liu,* Kemin Wang.* Dopamine modulated ionic permeability in mesoporous silica sphere based biomimetic compartment. Colloids and surfaces B: Biointerfaces, 2016, 142, 266–271.
[15] Jianbo Liu, Haining Ji, Jin Huang, Li Li, Qing Wang, Xiaohai Yang,* Kemin Wang.* Intelligent nucleic acid functionalized dual-responsive gold nanoflare: logic-gate nanodevice visualized by single-nanoparticle imaging. ChemistrySelect, 2016, 1(2), 347 –353
[14] Li Li, Jianbo Liu (co-author), Xiaohai Yang, Zhihong Peng, Wei Liu, Xu Jianguo, Jinglu Tang, Xiaoxiao He,* Kemin Wang.* Quantum dot/ methylene blue FRET mediated NIR fluorescent nanomicelles with large Stocks shift for bioimaging. Chemical Communications, 2015, 51, 14357-14360.
[13] Chunlei Wu, Jianbo Liu (co-author), Pengfei Zhang, Jing Li, Haining Ji, Xiaohai Yang, Kemin Wang* Recognition-before-labeling strategy for sensitive detection of lung cancer cells with quantum dots-aptamer complex. Analyst, 2015,140, 6100-6107.
[12] Wei Liu, Jianbo Liu (co-author), Xiaohai Yang, Kemin Wang,* Qing Wang, Meng Yang, Li Li, Chunxia Song. Phosphate modulated permeability of mesoporous silica spheres: a biomimetic ion channel decorated compartment model. Journal of Materials Chemistry B, 2015, 2015,3, 323-329.
[11] Jianbo Liu, Gui Li, Xiaohai Yang, Kemin Wang,* Li Li, Wei Liu, Xing Shi, Yali Guo. Exciton energy transfer-based quantum dot fluorescence sensing array: “chemical noses” for discrimination of different nucleobases. Analytical Chemistry, 2014, 87, 876-883.
[10] Jianbo Liu, Pengfei Zhang, Xiaohai Yang, Kemin Wang,* Qiuping Guo, Jin Huang, Wei Li. Aptamer-mediated indirect quantum dot labeling and fluorescent imaging of target proteins in living cells. Nanotechnology, 2014, 25, 505502.
[9] Jianbo Liu, Xiaohai Yang, Kemin Wang,* Qing Wang, Wei Liu, Dong Wang. Solid-phase single molecule biosensing using dual-color colocalization of fluorescent quantum dot nanoprobes. Nanoscale 2013, 5, 11257-11264.
[8] Jianbo Liu, Yan Liu, Xiaohai Yang, Kemin Wang,* Qing Wang, Hui Shi, Li Li. Exciton energy transfer-based fluorescent sensing through aptamer-programmed self-assembly of quantum dots. Analytical Chemistry 2013, 85, 11121-11128.
[7] Jianbo Liu, Xiaohai Yang, Kemin Wang,* Xiaoxiao He, Qing Wang, Jin Huang, Yan Liu. Aggregation control of quantum dots through ion-mediated hydrogen bonding shielding. ACS Nano, 2012, 6, 4973-4983.
[6] Jianbo Liu, Xiaohai Yang, Kemin Wang,* Qing Wang, Haining Ji, Chunlei Wu, Jing Li, Xiaoxiao He, Jinlu Tang, Jin Huang. Combining physical embedding and covalent bonding for stable encapsulation of quantum dots into agarose hydrogels. Journal of Materials Chemistry, 2012, 22, 495-501.
[5] Jianbo Liu, Xiaohai Yang, Kemin Wang,* Yan He, Pengfei Zhang, Haining Ji, Lixin Jian, Wei Liu. Single nanoparticle imaging and characterization of different phospholipid-encapsulated quantum dot micelles. Langmuir, 2012, 28, 10602-10609.
[4] Jianbo Liu, Xiaohai Yang, Kemin Wang,* Ronghua Yang, Haining Ji, Liyan Yang, Chunlei Wu. A switchable fluorescent quantum dot probe based on aggregation/disaggregation mechanism. Chemical Communications, 2011, 47, 935-937.
[3] Jianbo Liu, Xiaohai Yang, Xiaoxiao He, Kemin Wang,* Qing Wang, Qiuping Guo, Hui Shi, Jin Huang, Xiqin Huo. Fluorescent nanoparticles for chemical and biological sensing. Science China-Chemistry, 2011, 54, 1157-1176.
[2] Jianbo Liu, Xiaohai Yang, Kemin Wang,* Dong Wang, Pengfei Zhang. Chemical etching with tetrafluoroborate: a facile method for resizing of CdTe nanocrystals under mild conditions. Chemical Communications, 2009, 6080-6082.
[1] Jianbo Liu, Xiaohai Yang, Kemin Wang,* Weihong Tan, Zhaohui Li, Pengfei Zhang, Dong Wang. Preparation of hydrophobic quantum dots using oleylamine-hydrogen selenide complex as precursor. Chemical Journal of Chinese Universities, 2008, 29, 2516-2520.
[1] Ten Rising-Star Scientists in China (2021) ;
[2] Distinguished Young Talent at Hunan Province (2021);
[3] Excellent communist at Hunan University (2021);
[4] Outstanding Master's supervisor at Hunan Univrstiy (2017);
[5] Seal of Excellence Awarded to Outstanding Researchers under Marie Skłodowska-Curie Actions (2018);
[6] Yuelu scholar at Hunan University (2017);
[7] Outstanding Doctoral dissertation at Hunan University (2012).
Academic projects
Principal Investigator Projects:
[1] National Key R&D Program Subproject, 2023YFA0915402, "Synthetic Biology: Module Design and Intelligent Regulation of Cellular Hybrid Systems," 2024/01-2028/12.
[2] National Natural Science Foundation of China (NSFC) General Program, 22377025, "G-Quadruplex Artificial Transmembrane Channel-Mediated Potassium Ion Homeostasis Imbalance Induced Tumor Cell Apoptosis Study," 2024/01-2027/12.
[3] NSFC General Program, 22177032, "Hydrogen Sulfide Controlled Supply and Its Application in Vasodilation in Artificial Cells Based on Coacervate Vesicles," 2022/01-2025/12.
[4] NSFC General Program, 21778016, "Construction of Biomimetic Catalytic Nitric Oxide Producing Cascade Enzyme Assemblies and Their Antithrombotic Applications," 2018/01-2021/12.
[5] NSFC General Program, 21575037, "Construction of Nucleic Acid Aptamer-DNA Nanogel Drug Carriers and Their Tumor Targeting Therapeutic Study," 2016/01-2019/12.
[6] Hunan Province Innovation Platform and Talent Plan, 2022RC3047, "2022 Hunan Province Science and Technology Innovation Leading Talent," 2022/09-2025/09.
[7] NSFC Youth Fund, 21205033, "Construction of Quantum Dot Reversible Aggregation Fluorescent Nanoprobes," 2013/01-2015/12.
[8] Hunan Province Outstanding Youth Fund Project, 2021JJ10013, "Construction of Coacervate Artificial Cells and Their Nitric Oxide Production and Vasodilation Applications," 2021/01-2023/12.
[9] Hunan Provincial Natural Science Foundation General Program, 2020JJ4168, "Construction of Nitric Oxide Biomimetic Catalytic Assemblies and Their Biological Effects Study," 2020/01-2022/12.
[10] Hunan Provincial Natural Science Foundation Youth Project, 2017JJ3026, "Study on Serum Protein Sensing Technology Based on Quantum Dot Chemical Nose Array Map," 2017/01-2019/12.
[11] Hunan University Outstanding Youth Talent Cultivation Program Project, "Chemical Construction and Therapeutic Application of Artificial Cells," 2021/09-2023/09.
[12] National Key Laboratory of Chemo/Biosensing and Chemometrics Outstanding Youth Talent Cultivation Program Project, "Chemical Construction and Application of Artificial Cells," 2021/09-2022/09.
[13] National Key Laboratory of Chemo/Biosensing and Chemometrics Interdisciplinary Frontier Research Project, 2020/01-2021/01.
[14] Hunan University Young Teacher Growth Program Fund, "Basic Research Business Expenses of Central Universities, 2012-018," 2012/1-2018/12.
Participation Projects:
[15] Hunan Provincial Key R&D Science and Technology Program, 2017DK2011, "Construction of Mouse T-Stage In Situ Models and Functional Probe Screening for Early Diagnosis and Treatment of Colorectal Cancer and Their Targeted Therapeutic Applications," 2017/03-2019/12.
[16] 863 Program, "Development of Key Raw and Auxiliary Materials for Diagnostic Reagents," 2012/04-2016/12.
[17] NSFC Major Project Subproject, 21190041, "Screening of Nucleic Acid Aptamers and Molecular Recognition Basic Research," 2012/04-2016/12.
